Endocytosis of the IFNAR1 chain of Type 1 interferon receptor is regulated by diverse E2 ubiquitin conjugation enzymes

by Christopher J. Carbone, Hui Zheng, Serge Y. Fuchs
Published 2015-06-01

miR-216b regulation of c-Jun mediates GADD153/CHOP-dependent apoptosis

by Zhenhua Xu, Yiwen Bu, Nilesh Chitnis, Costas Koumenis, Serge Y. Fuchs, J. Alan Diehl
Published 2016-05-01

Microbiota-Driven Tonic Interferon Signals in Lung Stromal Cells Protect from Influenza Virus Infection

by Konrad C. Bradley, Katja Finsterbusch, Daniel Schnepf, Stefania Crotta, Miriam Llorian, Sophia Davidson, Serge Y. Fuchs, Peter Staeheli, Andreas Wack
Published 2019-07-01

Pathogen recognition receptor signaling accelerates phosphorylation-dependent degradation of IFNAR1.

by Juan Qian, Hui Zheng, Wei-Chun Huangfu, Jianghuai Liu, Christopher J Carbone, N Adrian Leu, Darren P Baker, Serge Y Fuchs
Published 2011-06-01

A BRISC-SHMT Complex Deubiquitinates IFNAR1 and Regulates Interferon Responses

by Hui Zheng, Vibhor Gupta, Jeffrey Patterson-Fortin, Sabyasachi Bhattacharya, Kanstantsin Katlinski, Junmin Wu, Bentley Varghese, Christopher J. Carbone, Bernadette Aressy, Serge Y. Fuchs, Roger A. Greenberg
Published 2013-10-01

Suppression of Type I Interferon Signaling Overcomes Oncogene-Induced Senescence and Mediates Melanoma Development and Progression

by Yuliya V. Katlinskaya, Kanstantsin V. Katlinski, Qiujing Yu, Angelica Ortiz, Daniel P. Beiting, Angela Brice, Diwakar Davar, Cindy Sanders, John M. Kirkwood, Hallgeir Rui, Xiaowei Xu, Constantinos Koumenis, J. Alan Diehl, Serge Y. Fuchs
Published 2016-04-01

DNA-Damage-Induced Type I Interferon Promotes Senescence and Inhibits Stem Cell Function

by Qiujing Yu, Yuliya V. Katlinskaya, Christopher J. Carbone, Bin Zhao, Kanstantsin V. Katlinski, Hui Zheng, Manti Guha, Ning Li, Qijun Chen, Ting Yang, Christopher J. Lengner, Roger A. Greenberg, F. Brad Johnson, Serge Y. Fuchs
Published 2015-05-01

PERK Is a Haploinsufficient Tumor Suppressor: Gene Dose Determines Tumor-Suppressive Versus Tumor Promoting Properties of PERK in Melanoma.

by Dariusz Pytel, Yan Gao, Katarzyna Mackiewicz, Yuliya V Katlinskaya, Kirk A Staschke, Maria C G Paredes, Akihiro Yoshida, Shuo Qie, Gao Zhang, Olga S Chajewski, Lawrence Wu, Ireneusz Majsterek, Meenhard Herlyn, Serge Y Fuchs, J Alan Diehl
Published 2016-12-01

Immune suppressive activity of myeloid-derived suppressor cells in cancer requires inactivation of the type I interferon pathway

by Kevin Alicea-Torres, Emilio Sanseviero, Jun Gui, Jinyun Chen, Filippo Veglia, Qiujin Yu, Laxminarasimha Donthireddy, Andrew Kossenkov, Cindy Lin, Shuyu Fu, Charles Mulligan, Brian Nam, Gregory Masters, Fred Denstman, Joseph Bennett, Neil Hockstein, Agnieszka Rynda-Apple, Yulia Nefedova, Serge Y. Fuchs, Dmitry I. Gabrilovich
Published 2021-03-01

Triggering ubiquitination of IFNAR1 protects tissues from inflammatory injury

by Sabyasachi Bhattacharya, Kanstantsin V Katlinski, Maximilian Reichert, Shigetsugu Takano, Angela Brice, Bin Zhao, Qiujing Yu, Hui Zheng, Christopher J Carbone, Yuliya V Katlinskaya, N Adrian Leu, Kelly A McCorkell, Satish Srinivasan, Melanie Girondo, Hallgeir Rui, Michael J May, Narayan G Avadhani, Anil K Rustgi, Serge Y Fuchs
Published 2014-03-01