The HIV-1 integrase α4-helix involved in LTR-DNA recognition is also a highly antigenic peptide element.

by Sandy Azzi, Vincent Parissi, Richard G Maroun, Pierre Eid, Olivier Mauffret, Serge Fermandjian
Published 2010-01-01

Unprocessed viral DNA could be the primary target of the HIV-1 integrase inhibitor raltegravir.

by Farah F Ammar, Safwat Abdel-Azeim, Loussinée Zargarian, Zeina Hobaika, Richard G Maroun, Serge Fermandjian
Published 2012-01-01

An unusual helix turn helix motif in the catalytic core of HIV-1 integrase binds viral DNA and LEDGF.

by Hayate Merad, Horea Porumb, Loussiné Zargarian, Brigitte René, Zeina Hobaika, Richard G Maroun, Olivier Mauffret, Serge Fermandjian
Published 2009-01-01

Spectrometric and computational studies of the binding of HIV-1 integrase inhibitors to viral DNA extremities

by Léa El Khoury, Krystel El Hage, Jean-Philip Piquemal, Serge Fermandjian, Richard G. Maroun, Nohad Gresh, Zeina Hobaika
Published 2019-12-01

Study of the inhibition mechanism of HIV-1 integrase by diketoacids molecules

by Léa El Khoury, Zeina Hobaika, Krystel El Hage, Serge Fermandjian, Jean-Philip Piquemal, Nohad Gresh, Richard G. Maroun
Published 2016-05-01