Leveraging the utility of pharmacogenomics in psychiatry through clinical decision support: a focus group study

by Andrew Goodspeed, Nicolas Kostman, Trenton E. Kriete, Joel W. Longtine, Sean M. Smith, Peregrin Marshall, Wesley Williams, Cheryl Clark, Weston W. Blakeslee
Published 2019-08-01

Early intervention of tau pathology prevents behavioral changes in the rTg4510 mouse model of tauopathy.

by Xiaohai Wang, Karen Smith, Michelle Pearson, Anna Hughes, Mali L Cosden, Jacob Marcus, J Fred Hess, Mary J Savage, Thomas Rosahl, Sean M Smith, Joel B Schachter, Jason M Uslaner
Published 2018-01-01

LRRK2 inhibition prevents endolysosomal deficits seen in human Parkinson's disease

by Emily M. Rocha, Briana R. De Miranda, Sandra Castro, Robert Drolet, Nathan G. Hatcher, Lihang Yao, Sean M. Smith, Matthew T. Keeney, Roberto Di Maio, Julia Kofler, Teresa G. Hastings, J. Timothy Greenamyre
Published 2020-02-01

A novel glucosylceramide synthase inhibitor attenuates alpha synuclein pathology and lysosomal dysfunction in preclinical models of synucleinopathy

by Mali Cosden, Sarah Jinn, Lihang Yao, Cheryl A. Gretzula, Monika Kandebo, Dawn Toolan, Nathan G. Hatcher, Lei Ma, Wei Lemaire, Gregory C. Adam, Christine Burlein, Christina Minnick, Rose Flick, Marla L. Watt, James Mulhearn, Mark Fraley, Robert E. Drolet, Jacob N. Marcus, Sean M. Smith
Published 2021-11-01