Strategies to Use Nanoparticles to Generate CD4 and CD8 Regulatory T Cells for the Treatment of SLE and Other Autoimmune Diseases

by David A. Horwitz, David A. Horwitz, Sean Bickerton, Antonio La Cava
Published 2021-06-01

Nanoparticles Engineered as Artificial Antigen-Presenting Cells Induce Human CD4+ and CD8+ Tregs That Are Functional in Humanized Mice

by Sophia Giang, David A. Horwitz, David A. Horwitz, Sean Bickerton, Antonio La Cava
Published 2021-05-01

Multiple Sclerosis: LIFNano-CD4 for Trojan Horse Delivery of the Neuro-Protective Biologic “LIF” Into the Brain: Preclinical Proof of Concept

by Raul de la Flor, Janette Robertson, Rostislav V. Shevchenko, Mo Alavijeh, Sean Bickerton, Tarek Fahmy, Su M. Metcalfe
Published 2021-04-01

Anti-CD2 Antibody-Coated Nanoparticles Containing IL-2 Induce NK Cells That Protect Lupus Mice via a TGF-β-Dependent Mechanism

by David A. Horwitz, David A. Horwitz, Aijing Liu, Sean Bickerton, Giuseppe Castaldo, Giuseppe Matarese, Giuseppe Matarese, Tarek M. Fahmy, Tarek M. Fahmy, Antonio La Cava
Published 2020-12-01