Transforming growth factor β neutralization ameliorates pre-existing hepatic fibrosis and reduces cholangiocarcinoma in thioacetamide-treated rats.

by Hong Ling, Eric Roux, Donna Hempel, Jingzang Tao, Mandy Smith, Scott Lonning, Anna Zuk, Cynthia Arbeeny, Steve Ledbetter
Published 2013-01-01

Anti-transforming growth factor ß antibody treatment rescues bone loss and prevents breast cancer metastasis to bone.

by Swati Biswas, Jeffry S Nyman, JoAnn Alvarez, Anwesa Chakrabarti, Austin Ayres, Julie Sterling, James Edwards, Tapasi Rana, Rachelle Johnson, Daniel S Perrien, Scott Lonning, Yu Shyr, Lynn M Matrisian, Gregory R Mundy
Published 2011-01-01

TGF-β regulates DNA methyltransferase expression in prostate cancer, correlates with aggressive capabilities, and predicts disease recurrence.

by Qiang Zhang, Lin Chen, Brian T Helfand, Thomas L Jang, Vidit Sharma, James Kozlowski, Timothy Michael Kuzel, Lihua J Zhu, Ximing J Yang, Borko Javonovic, Yinglu Guo, Scott Lonning, Jay Harper, Beverly A Teicher, Charles Brendler, Nengwang Yu, William J Catalona, Chung Lee
Published 2011-01-01