One-step construction of circularized nanodiscs using SpyCatcher-SpyTag

by Shanwen Zhang, Qian Ren, Scott J. Novick, Timothy S. Strutzenberg, Patrick R. Griffin, Huan Bao
Published 2021-09-01

Structures of the human LONP1 protease reveal regulatory steps involved in protease activation

by Mia Shin, Edmond R. Watson, Albert S. Song, Jeffrey T. Mindrebo, Scott J. Novick, Patrick R. Griffin, R. Luke Wiseman, Gabriel C. Lander
Published 2021-05-01

Structural organization of a major neuronal G protein regulator, the RGS7-Gβ5-R7BP complex

by Dipak N Patil, Erumbi S Rangarajan, Scott J Novick, Bruce D Pascal, Douglas J Kojetin, Patrick R Griffin, Tina Izard, Kirill A Martemyanov
Published 2018-12-01

Structural and Dynamic Elucidation of a Non-acid PPARγ Partial Agonist: SR1988

by Rebecca L. Frkic, Benjamin S. Chua, Youseung Shin, Bruce D. Pascal, Scott J. Novick, Theodore M. Kamenecka, Patrick R. Griffin, John B. Bruning
Published 2018-09-01

Correction: HDX-MS reveals structural determinants for RORγ hyperactivation by synthetic agonists

by Timothy S Strutzenberg, Ruben D Garcia-Ordonez, Scott J Novick, HaJeung Park, Mi Ra Chang, Christelle Doebellin, Yuanjun He, Rémi Patouret, Theodore M Kamenecka, Patrick R Griffin
Published 2019-10-01

HDX-MS reveals structural determinants for RORγ hyperactivation by synthetic agonists

by Timothy S Strutzenberg, Ruben D Garcia-Ordonez, Scott J Novick, HaJeung Park, Mi Ra Chang, Christelle Doebellin, Yuanjun He, Rémi Patouret, Theodore M Kamenecka, Patrick R Griffin
Published 2019-06-01

Definition of functionally and structurally distinct repressive states in the nuclear receptor PPARγ

by Zahra Heidari, Ian M. Chrisman, Michelle D. Nemetchek, Scott J. Novick, Anne-Laure Blayo, Trey Patton, Desiree E. Mendes, Philippe Diaz, Theodore M. Kamenecka, Patrick R. Griffin, Travis S. Hughes
Published 2019-12-01

HDX-MS reveals dysregulated checkpoints that compromise discrimination against self RNA during RIG-I mediated autoimmunity

by Jie Zheng, Chen Wang, Mi Ra Chang, Swapnil C. Devarkar, Brandon Schweibenz, Gogce C. Crynen, Ruben D. Garcia-Ordonez, Bruce D. Pascal, Scott J. Novick, Smita S. Patel, Joseph Marcotrigiano, Patrick R. Griffin
Published 2018-12-01

HDX reveals the conformational dynamics of DNA sequence specific VDR co-activator interactions

by Jie Zheng, Mi Ra Chang, Ryan E. Stites, Yong Wang, John B. Bruning, Bruce D. Pascal, Scott J. Novick, Ruben D. Garcia-Ordonez, Keith R. Stayrook, Michael J. Chalmers, Jeffrey A. Dodge, Patrick R. Griffin
Published 2017-10-01

Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation

by Sean W Fanning, Christopher G Mayne, Venkatasubramanian Dharmarajan, Kathryn E Carlson, Teresa A Martin, Scott J Novick, Weiyi Toy, Bradley Green, Srinivas Panchamukhi, Benita S Katzenellenbogen, Emad Tajkhorshid, Patrick R Griffin, Yang Shen, Sarat Chandarlapaty, John A Katzenellenbogen, Geoffrey L Greene
Published 2016-02-01