Hippo signaling effectors YAP and TAZ induce Epstein-Barr Virus (EBV) lytic reactivation through TEADs in epithelial cells.

by Nicholas Van Sciver, Makoto Ohashi, Nicholas P Pauly, Jillian A Bristol, Scott E Nelson, Eric C Johannsen, Shannon C Kenney
Published 2021-08-01

EBNA2-deleted Epstein-Barr virus (EBV) isolate, P3HR1, causes Hodgkin-like lymphomas and diffuse large B cell lymphomas with type II and Wp-restricted latency types in humanized mi...

by Chunrong Li, James C Romero-Masters, Shane Huebner, Makoto Ohashi, Mitchell Hayes, Jillian A Bristol, Scott E Nelson, Mark R Eichelberg, Nicholas Van Sciver, Erik A Ranheim, Rona S Scott, Eric C Johannsen, Shannon C Kenney
Published 2020-06-01

B cells infected with Type 2 Epstein-Barr virus (EBV) have increased NFATc1/NFATc2 activity and enhanced lytic gene expression in comparison to Type 1 EBV infection.

by James C Romero-Masters, Shane M Huebner, Makoto Ohashi, Jillian A Bristol, Bayleigh E Benner, Elizabeth A Barlow, Gail L Turk, Scott E Nelson, Dana C Baiu, Nicholas Van Sciver, Erik A Ranheim, Jenny Gumperz, Nathan M Sherer, Paul J Farrell, Eric C Johannsen, Shannon C Kenney
Published 2020-02-01