Arid1a restrains Kras-dependent changes in acinar cell identity

by Geulah Livshits, Direna Alonso-Curbelo, John P Morris IV, Richard Koche, Michael Saborowski, John Erby Wilkinson, Scott W Lowe
Published 2018-07-01

Targeting Synthetic Lethal Interactions between Myc and the eIF4F Complex Impedes Tumorigenesis

by Chen-Ju Lin, Zeina Nasr, Prem K. Premsrirut, John A. Porco, Jr., Yoshitaka Hippo, Scott W. Lowe, Jerry Pelletier
Published 2012-04-01

Acquired Dependence of Acute Myeloid Leukemia on the DEAD-Box RNA Helicase DDX5

by Anthony Mazurek, Youngkyu Park, Cornelius Miething, John E. Wilkinson, Jesse Gillis, Scott W. Lowe, Christopher R. Vakoc, Bruce Stillman
Published 2014-06-01

Conditional reverse tet-transactivator mouse strains for the efficient induction of TRE-regulated transgenes in mice.

by Lukas E Dow, Zeina Nasr, Michael Saborowski, Saya H Ebbesen, Eusebio Manchado, Nilgun Tasdemir, Teresa Lee, Jerry Pelletier, Scott W Lowe
Published 2014-01-01

Inducible In Vivo Silencing of Brd4 Identifies Potential Toxicities of Sustained BET Protein Inhibition

by Jessica E. Bolden, Nilgun Tasdemir, Lukas E. Dow, Johan H. van Es, John E. Wilkinson, Zhen Zhao, Hans Clevers, Scott W. Lowe
Published 2014-09-01

Variability of inducible expression across the hematopoietic system of tetracycline transactivator transgenic mice.

by Megumi Takiguchi, Lukas E Dow, Julia E Prier, Catherine L Carmichael, Benjamin T Kile, Stephen J Turner, Scott W Lowe, David C S Huang, Ross A Dickins
Published 2013-01-01

Reversible suppression of cyclooxygenase 2 (COX-2) expression in vivo by inducible RNA interference.

by Anne K Zaiss, Johannes Zuber, Chun Chu, Hidevaldo B Machado, Jing Jiao, Arthur B Catapang, Tomo-o Ishikawa, Jose S Gil, Scott W Lowe, Harvey R Herschman
Published 2014-01-01

Correction: TP53 exon-6 truncating mutations produce separation of function isoforms with pro-tumorigenic functions

by Nitin H Shirole, Debjani Pal, Edward R Kastenhuber, Serif Senturk, Joseph Boroda, Paola Pisterzi, Madison Miller, Gustavo Munoz, Marko Anderluh, Marc Ladanyi, Scott W Lowe, Raffaella Sordella
Published 2017-02-01

TP53 exon-6 truncating mutations produce separation of function isoforms with pro-tumorigenic functions

by Nitin H Shirole, Debjani Pal, Edward R Kastenhuber, Serif Senturk, Joseph Boroda, Paola Pisterzi, Madison Miller, Gustavo Munoz, Marko Anderluh, Marc Ladanyi, Scott W Lowe, Raffaella Sordella
Published 2016-10-01

Reciprocal interaction of Wnt and RXR-α pathways in hepatocyte development and hepatocellular carcinoma.

by Jinyu Li, Maia Chanrion, Eric Sawey, Tim Wang, Edward Chow, Aaron Tward, Yi Su, Wen Xue, Robert Lucito, Lars Zender, Scott W Lowe, J Michael Bishop, Scott Powers
Published 2015-01-01

Chromatin-informed inference of transcriptional programs in gynecologic and basal breast cancers

by Hatice U. Osmanbeyoglu, Fumiko Shimizu, Angela Rynne-Vidal, Direna Alonso-Curbelo, Hsuan-An Chen, Hannah Y. Wen, Tsz-Lun Yeung, Petar Jelinic, Pedram Razavi, Scott W. Lowe, Samuel C. Mok, Gabriela Chiosis, Douglas A. Levine, Christina S. Leslie
Published 2019-09-01

Gene mutations and genomic rearrangements in the mouse as a result of transposon mobilization from chromosomal concatemers.

by Aron M Geurts, Lara S Collier, Jennifer L Geurts, Leann L Oseth, Matthew L Bell, David Mu, Robert Lucito, Susan A Godbout, Laura E Green, Scott W Lowe, Betsy A Hirsch, Leslie A Leinwand, David A Largaespada
Published 2006-09-01

MicroRNA-375 Suppresses the Growth and Invasion of Fibrolamellar CarcinomaSummary

by Timothy A. Dinh, Mark L. Jewell, Matt Kanke, Adam Francisco, Ramja Sritharan, Rigney E. Turnham, Seona Lee, Edward R. Kastenhuber, Eliane Wauthier, Cynthia D. Guy, Raymond S. Yeung, Scott W. Lowe, Lola M. Reid, John D. Scott, Anna M. Diehl, Praveen Sethupathy
Published 2019-01-01

Two Distinct Categories of Focal Deletions in Cancer Genomes.

by Megha Rajaram, Jianping Zhang, Tim Wang, Jinyu Li, Cem Kuscu, Huan Qi, Mamoru Kato, Vladimir Grubor, Robert J Weil, Aslaug Helland, Anne-Lise Borrenson-Dale, Kathleen R Cho, Douglas A Levine, Alan N Houghton, Jedd D Wolchok, Lois Myeroff, Sanford D Markowitz, Scott W Lowe, Michael Zhang, Alex Krasnitz, Robert Lucito, David Mu, R Scott Powers
Published 2013-01-01

Differential Effector Engagement by Oncogenic KRAS

by Tina L. Yuan, Arnaud Amzallag, Rachel Bagni, Ming Yi, Shervin Afghani, William Burgan, Nicole Fer, Leslie A. Strathern, Katie Powell, Brian Smith, Andrew M. Waters, David Drubin, Ty Thomson, Rosy Liao, Patricia Greninger, Giovanna T. Stein, Ellen Murchie, Eliane Cortez, Regina K. Egan, Lauren Procter, Matthew Bess, Kwong Tai Cheng, Chih-Shia Lee, Liam Changwoo Lee, Christof Fellmann, Robert Stephens, Ji Luo, Scott W. Lowe, Cyril H. Benes, Frank McCormick
Published 2018-02-01