Thermodynamic and computational analyses reveal the functional roles of the galloyl group of tea catechins in molecular recognition.

by Tomoya Takahashi, Satoru Nagatoishi, Daisuke Kuroda, Kouhei Tsumoto
Published 2018-01-01

Structural and Functional Characterization of RecG Helicase under Dilute and Molecular Crowding Conditions

by Sarika Saxena, Satoru Nagatoishi, Daisuke Miyoshi, Naoki Sugimoto
Published 2012-01-01

Highly sensitive biomolecular interaction detection method using optical bound/free separation with grating-coupled surface plasmon field-enhanced fluorescence spectroscopy (GC-SPF...

by Takatoshi Kaya, Satoru Nagatoishi, Kosuke Nagae, Yukito Nakamura, Kohei Tsumoto
Published 2019-01-01

A glutamine sensor that directly activates TORC1

by Mirai Tanigawa, Katsuyoshi Yamamoto, Satoru Nagatoishi, Koji Nagata, Daisuke Noshiro, Nobuo N. Noda, Kouhei Tsumoto, Tatsuya Maeda
Published 2021-09-01

Affinity improvement of a therapeutic antibody by structure-based computational design: generation of electrostatic interactions in the transition state stabilizes the antibody-ant...

by Masato Kiyoshi, Jose M M Caaveiro, Eri Miura, Satoru Nagatoishi, Makoto Nakakido, Shinji Soga, Hiroki Shirai, Shigeki Kawabata, Kouhei Tsumoto
Published 2014-01-01

Structural basis for selective inhibition of human serine hydroxymethyltransferase by secondary bile acid conjugate

by Tomoki Ota, Akinobu Senoo, Masumi Shirakawa, Hiroshi Nonaka, Yutaro Saito, Sho Ito, Go Ueno, Satoru Nagatoishi, Kouhei Tsumoto, Shinsuke Sando
Published 2021-02-01

Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion

by Akinobu Senoo, Sho Ito, Satoru Nagatoishi, Yutaro Saito, Go Ueno, Daisuke Kuroda, Kouhei Yoshida, Takumi Tashima, Shota Kudo, Shinsuke Sando, Kouhei Tsumoto
Published 2021-09-01

Heme controls the structural rearrangement of its sensor protein mediating the hemolytic bacterial survival

by Megumi Nishinaga, Hiroshi Sugimoto, Yudai Nishitani, Seina Nagai, Satoru Nagatoishi, Norifumi Muraki, Takehiko Tosha, Kouhei Tsumoto, Shigetoshi Aono, Yoshitsugu Shiro, Hitomi Sawai
Published 2021-04-01

Design strategy for serine hydroxymethyltransferase probes based on retro-aldol-type reaction

by Hiroshi Nonaka, Yuki Nakanishi, Satoshi Kuno, Tomoki Ota, Kentaro Mochidome, Yutaro Saito, Fuminori Sugihara, Yoichi Takakusagi, Ichio Aoki, Satoru Nagatoishi, Kouhei Tsumoto, Shinsuke Sando
Published 2019-02-01

A secondary RET mutation in the activation loop conferring resistance to vandetanib

by Takashi Nakaoku, Takashi Kohno, Mitsugu Araki, Seiji Niho, Rakhee Chauhan, Phillip P. Knowles, Katsuya Tsuchihara, Shingo Matsumoto, Yoko Shimada, Sachiyo Mimaki, Genichiro Ishii, Hitoshi Ichikawa, Satoru Nagatoishi, Kouhei Tsumoto, Yasushi Okuno, Kiyotaka Yoh, Neil Q. McDonald, Koichi Goto
Published 2018-02-01