Aberrant proliferation in CXCR7+ endothelial cells via degradation of the retinoblastoma protein.

by Jennifer E Totonchy, Jessica M Osborn, Sara Botto, Lisa Clepper, Ashlee V Moses
Published 2013-01-01

Herpes simplex virus type 1 inflammasome activation in proinflammatory human macrophages is dependent on NLRP3, ASC, and caspase-1.

by Andrew H Karaba, Alexis Figueroa, Guido Massaccesi, Sara Botto, Victor R DeFilippis, Andrea L Cox
Published 2020-01-01

A replicating cytomegalovirus-based vaccine encoding a single Ebola virus nucleoprotein CTL epitope confers protection against Ebola virus.

by Yoshimi Tsuda, Patrizia Caposio, Christopher J Parkins, Sara Botto, Ilhem Messaoudi, Luka Cicin-Sain, Heinz Feldmann, Michael A Jarvis
Published 2011-08-01

Human Cytomegalovirus Immediate Early 86-kDa Protein Blocks Transcription and Induces Degradation of the Immature Interleukin-1β Protein during Virion-Mediated Activation of the AI...

by Sara Botto, Jinu Abraham, Nobuyo Mizuno, Kara Pryke, Bryan Gall, Igor Landais, Daniel N. Streblow, Klaus J. Fruh, Victor R. DeFilippis
Published 2019-02-01

Characterization of a Novel Compound That Stimulates STING-Mediated Innate Immune Activity in an Allele-Specific Manner

by Jinu Abraham, Sara Botto, Nobuyo Mizuno, Kara Pryke, Bryan Gall, Dylan Boehm, Tina M. Sali, Haihong Jin, Aaron Nilsen, Michael Gough, Jason Baird, Marita Chakhtoura, Caroline Subra, Caroline Subra, Lydie Trautmann, Elias K. Haddad, Victor R. DeFilippis
Published 2020-07-01