NF-κB inducing kinase, NIK mediates cigarette smoke/TNFα-induced histone acetylation and inflammation through differential activation of IKKs.

by Sangwoon Chung, Isaac K Sundar, Jae-Woong Hwang, Fiona E Yull, Timothy S Blackwell, Vuokko L Kinnula, Michael Bulger, Hongwei Yao, Irfan Rahman
Published 2011-01-01

PolyADP-Ribosylation of NFATc3 and NF-κB Transcription Factors Modulate Macrophage Inflammatory Gene Expression in LPS-Induced Acute Lung Injury

by Yunjuan Nie, Teja Srinivas Nirujogi, Ravi Ranjan, Brenda F. Reader, Sangwoon Chung, Megan N. Ballinger, Joshua A. Englert, John W. Christman, Manjula Karpurapu
Published 2020-10-01

Mitogen- and stress-activated kinase 1 (MSK1) regulates cigarette smoke-induced histone modifications on NF-κB-dependent genes.

by Isaac K Sundar, Sangwoon Chung, Jae-Woong Hwang, John D Lapek, Michael Bulger, Alan E Friedman, Hongwei Yao, James R Davie, Irfan Rahman
Published 2012-01-01

Krüppel like factor 4 promoter undergoes active demethylation during monocyte/macrophage differentiation.

by Manjula Karpurapu, Ravi Ranjan, Jing Deng, Sangwoon Chung, Yong Gyu Lee, Lei Xiao, Teja Srinivas Nirujogi, Jeffrey R Jacobson, Gye Young Park, John W Christman
Published 2014-01-01

MicroRNA-138 suppresses glioblastoma proliferation through downregulation of CD44

by Margaret Yeh, Yin-Ying Wang, Ji Young Yoo, Christina Oh, Yoshihiro Otani, Jin Muk Kang, Eun S. Park, Eunhee Kim, Sangwoon Chung, Young-Jun Jeon, George A. Calin, Balveen Kaur, Zhongming Zhao, Tae Jin Lee
Published 2021-04-01

A kinome-wide screen identifies a CDKL5-SOX9 regulatory axis in epithelial cell death and kidney injury

by Ji Young Kim, Yuntao Bai, Laura A. Jayne, Ralph D. Hector, Avinash K. Persaud, Su Sien Ong, Shreshtha Rojesh, Radhika Raj, Mei Ji He Ho Feng, Sangwoon Chung, Rachel E. Cianciolo, John W. Christman, Moray J. Campbell, David S. Gardner, Sharyn D. Baker, Alex Sparreboom, Rajgopal Govindarajan, Harpreet Singh, Taosheng Chen, Ming Poi, Katalin Susztak, Stuart R. Cobb, Navjot Singh Pabla
Published 2020-04-01