The mitochondrial DNA polymerase gamma degrades linear DNA fragments precluding the formation of deletions

by Nadee Nissanka, Sandra R. Bacman, Melanie J. Plastini, Carlos T. Moraes
Published 2018-06-01

Myopathy reversion in mice after restauration of mitochondrial complex I

by Claudia V Pereira, Susana Peralta, Tania Arguello, Sandra R Bacman, Francisca Diaz, Carlos T Moraes
Published 2020-02-01

mitoTev‐TALE: a monomeric DNA editing enzyme to reduce mutant mitochondrial DNA levels

by Claudia V Pereira, Sandra R Bacman, Tania Arguello, Ugne Zekonyte, Sion L Williams, David R Edgell, Carlos T Moraes
Published 2018-09-01

Mitochondrial targeted meganuclease as a platform to eliminate mutant mtDNA in vivo

by Ugne Zekonyte, Sandra R. Bacman, Jeff Smith, Wendy Shoop, Claudia V. Pereira, Ginger Tomberlin, James Stewart, Derek Jantz, Carlos T. Moraes
Published 2021-05-01