Antagonizing Retinoic Acid-Related-Orphan Receptor Gamma Activity Blocks the T Helper 17/Interleukin-17 Pathway Leading to Attenuated Pro-inflammatory Human Keratinocyte and Skin R...

by Florence Ecoeur, Jessica Weiss, Klemens Kaupmann, Samuel Hintermann, David Orain, Christine Guntermann
Published 2019-03-01

Effects of isoxazolo-pyridinone 7e, a potent activator of the Nurr1 signaling pathway, on experimental autoimmune encephalomyelitis in mice.

by Francesca Montarolo, Chiara Raffaele, Simona Perga, Serena Martire, Annamaria Finardi, Roberto Furlan, Samuel Hintermann, Antonio Bertolotto
Published 2014-01-01

Pharmacological inhibition of RORγt suppresses the Th17 pathway and alleviates arthritis in vivo.

by Ulf Guendisch, Jessica Weiss, Florence Ecoeur, Julia Christina Riker, Klemens Kaupmann, Joerg Kallen, Samuel Hintermann, David Orain, Janet Dawson, Andreas Billich, Christine Guntermann
Published 2017-01-01