Therapeutic opportunities for pain medicines via targeting of specific translation signaling mechanisms

by Salim Megat, Theodore J. Price
Published 2018-08-01

Inhibition of Poly(A)-binding protein with a synthetic RNA mimic reduces pain sensitization in mice

by Paulino Barragán-Iglesias, Tzu-Fang Lou, Vandita D. Bhat, Salim Megat, Michael D. Burton, Theodore J. Price, Zachary T. Campbell
Published 2018-01-01

Temporal and sex differences in the role of BDNF/TrkB signaling in hyperalgesic priming in mice and rats

by Jamie K. Moy, Thomas Szabo-Pardi, Dipti V. Tillu, Salim Megat, Grishma Pradhan, Moeno Kume, Marina N. Asiedu, Michael D. Burton, Gregory Dussor, Theodore J. Price
Published 2019-01-01

Antidepressants suppress neuropathic pain by a peripheral β2-adrenoceptor mediated anti-TNFα mechanism

by Yohann Bohren, Luc-Henri Tessier, Salim Megat, Hugues Petitjean, Sylvain Hugel, Dorothée Daniel, Mélanie Kremer, Sylvie Fournel, Lutz Hein, Rémy Schlichter, Marie-José Freund-Mercier, Ipek Yalcin, Michel Barrot
Published 2013-12-01

Synaptic FUS accumulation triggers early misregulation of synaptic RNAs in a mouse model of ALS

by Sonu Sahadevan, Katharina M. Hembach, Elena Tantardini, Manuela Pérez-Berlanga, Marian Hruska-Plochan, Salim Megat, Julien Weber, Petra Schwarz, Luc Dupuis, Mark D. Robinson, Pierre De Rossi, Magdalini Polymenidou
Published 2021-05-01

Sex differences in the role of atypical PKC within the basolateral nucleus of the amygdala in a mouse hyperalgesic priming model

by Daniela Baptista-de-Souza, Diana Tavares-Ferreira, Salim Megat, Ishwarya Sankaranarayanan, Stephanie Shiers, Christopher M. Flores, Sourav Ghosh, Ricardo Luiz Nunes-de-Souza, Azair Canto-de-Souza, Theodore J. Price
Published 2020-08-01

Wild-type FUS corrects ALS-like disease induced by cytoplasmic mutant FUS through autoregulation

by Inmaculada Sanjuan-Ruiz, Noé Govea-Perez, Melissa McAlonis-Downes, Stéphane Dieterle, Salim Megat, Sylvie Dirrig-Grosch, Gina Picchiarelli, Diana Piol, Qiang Zhu, Brian Myers, Chao-Zong Lee, Don W Cleveland, Clotilde Lagier-Tourenne, Sandrine Da Cruz, Luc Dupuis
Published 2021-09-01

Cytoplasmic FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and inhibitory synaptic defects

by Jelena Scekic-Zahirovic, Inmaculada Sanjuan-Ruiz, Vanessa Kan, Salim Megat, Pierre De Rossi, Stéphane Dieterlé, Raphaelle Cassel, Marguerite Jamet, Pascal Kessler, Diana Wiesner, Laura Tzeplaeff, Valérie Demais, Sonu Sahadevan, Katharina M. Hembach, Hans-Peter Muller, Gina Picchiarelli, Nibha Mishra, Stefano Antonucci, Sylvie Dirrig-Grosch, Jan Kassubek, Volker Rasche, Albert Ludolph, Anne-Laurence Boutillier, Francesco Roselli, Magdalini Polymenidou, Clotilde Lagier-Tourenne, Sabine Liebscher, Luc Dupuis
Published 2021-05-01