Aging-like Phenotype and Defective Lineage Specification in SIRT1-Deleted Hematopoietic Stem and Progenitor Cells

by Pauline Rimmelé, Carolina L. Bigarella, Raymond Liang, Brigitte Izac, Rebeca Dieguez-Gonzalez, Gaetan Barbet, Michael Donovan, Carlo Brugnara, Julie M. Blander, David A. Sinclair, Saghi Ghaffari
Published 2014-07-01

A Systems Approach Identifies Essential FOXO3 Functions at Key Steps of Terminal Erythropoiesis.

by Raymond Liang, Genís Campreciós, Yan Kou, Kathleen McGrath, Roberta Nowak, Seana Catherman, Carolina L Bigarella, Pauline Rimmelé, Xin Zhang, Merlin Nithya Gnanapragasam, James J Bieker, Dmitri Papatsenko, Avi Ma'ayan, Emery Bresnick, Velia Fowler, James Palis, Saghi Ghaffari
Published 2015-10-01

Targeting the BRD4/FOXO3a/CDK6 axis sensitizes AKT inhibition in luminal breast cancer

by Jingyi Liu, Zhibing Duan, Weijie Guo, Lei Zeng, Yadi Wu, Yule Chen, Fang Tai, Yifan Wang, Yiwei Lin, Qiang Zhang, Yanling He, Jiong Deng, Rachel L. Stewart, Chi Wang, Pengnian Charles Lin, Saghi Ghaffari, B. Mark Evers, Suling Liu, Ming-Ming Zhou, Binhua P. Zhou, Jian Shi
Published 2018-12-01