Identification of cis-acting elements and splicing factors involved in the regulation of BIM Pre-mRNA splicing.

by Wen Chun Juan, Xavier Roca, S Tiong Ong
Published 2014-01-01

The HDAC inhibitor SB939 overcomes resistance to BCR-ABL kinase Inhibitors conferred by the BIM deletion polymorphism in chronic myeloid leukemia.

by Muhammad Rauzan, Charles T H Chuah, Tun Kiat Ko, S Tiong Ong
Published 2017-01-01

Multi-agent chemotherapy overcomes glucocorticoid resistance conferred by a BIM deletion polymorphism in pediatric acute lymphoblastic leukemia.

by Sheila Xinxuan Soh, Joshua Yew Suang Lim, John W J Huang, Nan Jiang, Allen Eng Juh Yeoh, S Tiong Ong
Published 2014-01-01

A novel Bcr-Abl–mTOR–eIF4A axis regulates IRES-mediated translation of LEF-1

by Becky Pinjou Tsai, Judith Jimenez, Sharon Lim, Kerry D. Fitzgerald, Min Zhang, Charles T. H. Chuah, Haley Axelrod, Luke Nelson, S. Tiong Ong, Bert L. Semler, Marian L. Waterman
Published 2014-01-01

The arginase inhibitor Nω-hydroxy-nor-arginine (nor-NOHA) induces apoptosis in leukemic cells specifically under hypoxic conditions but CRISPR/Cas9 excludes arginase 2 (ARG2) as th...

by King Pan Ng, Aditi Manjeri, Lin Ming Lee, Zhu En Chan, Chin Yee Tan, Qiancheng Darren Tan, A'Qilah Majeed, Kian Leong Lee, Charles Chuah, Toshio Suda, S Tiong Ong
Published 2018-01-01