Whole Genome Analysis of Ovarian Granulosa Cell Tumors Reveals Tumor Heterogeneity and a High-Grade TP53-Specific Subgroup

by Joline Roze, Glen Monroe, Joachim Kutzera, Jolijn Groeneweg, Ellen Stelloo, Sterre Paijens, Hans Nijman, Hannah van Meurs, Luc van Lonkhuijzen, Jurgen Piek, Christianne Lok, Geertruida Jonges, Petronella Witteveen, René Verheijen, Gijs van Haaften, Ronald Zweemer
Published 2020-05-01

In Vitro Systematic Drug Testing Reveals Carboplatin, Paclitaxel, and Alpelisib as a Potential Novel Combination Treatment for Adult Granulosa Cell Tumors

by Joline Roze, Elena Sendino Garví, Ellen Stelloo, Christina Stangl, Ferdinando Sereno, Karen Duran, Jolijn Groeneweg, Sterre Paijens, Hans Nijman, Hannah van Meurs, Luc van Lonkhuijzen, Jurgen Piek, Christianne Lok, Geertruida Jonges, Petronella Witteveen, René Verheijen, Gijs van Haaften, Ronald Zweemer, Glen Monroe
Published 2021-01-01

Deep immune profiling of ovarian tumors identifies minimal MHC-I expression after neoadjuvant chemotherapy as negatively associated with T-cell-dependent outcome

by Kim L. Brunekreeft, Sterre T. Paijens, Maartje C.A. Wouters, Fenne L. Komdeur, Florine A. Eggink, Joyce M. Lubbers, Hagma H. Workel, Elisabeth C. Van Der Slikke, Noor E.J. Pröpper, Ninke Leffers, Julien Adam, Harry Pijper, Annechien Plat, Arjan Kol, Hans W. Nijman, Marco De Bruyn
Published 2020-01-01

Prognostic image-based quantification of CD8CD103 T cell subsets in high-grade serous ovarian cancer patients

by S. T. Paijens, A. Vledder, D. Loiero, E. W. Duiker, J. Bart, A. M. Hendriks, M. Jalving, H. H. Workel, H. Hollema, N. Werner, A. Plat, G. B. A. Wisman, R. Yigit, H. Arts, A. J. Kruse, N.M. de Lange, V. H. Koelzer, M. de Bruyn, H. W. Nijman
Published 2021-01-01