A general pharmacodynamic interaction model identifies perpetrators and victims in drug interactions

by Sebastian G. Wicha, Chunli Chen, Oskar Clewe, Ulrika S. H. Simonsson
Published 2017-12-01

A Model-Based Pharmacokinetic/Pharmacodynamic Analysis of the Combination of Amoxicillin and Monophosphoryl Lipid A Against <i>S. pneumoniae</i> in Mice

by Sebastian Franck, Robin Michelet, Fiordiligie Casilag, Jean-Claude Sirard, Sebastian G. Wicha, Charlotte Kloft
Published 2021-03-01

Tigecycline in critically ill patients on continuous renal replacement therapy: a population pharmacokinetic study

by A. Broeker, S. G. Wicha, C. Dorn, A. Kratzer, M. Schleibinger, F. Kees, A. Heininger, M. G. Kees, H. Häberle
Published 2018-12-01

Pharmacokinetics of tigecycline in critically ill patients with liver failure defined by maximal liver function capacity test (LiMAx)

by Rawan Alraish, Sebastian G. Wicha, Otto R. Frey, Anka C. Roehr, Johann Pratschke, Martin Stockmann, Tilo Wuensch, Magnus Kaffarnik
Published 2020-08-01

In vivo / in vitro Correlation of Pharmacokinetics of Gentamicin, Vancomycin, Teicoplanin and Doripenem in a Bovine Blood Hemodialysis Model

by M G Vossen, S Pferschy, C Milacek, M Haidinger, Mario Karolyi, Zoltan Vass, Heinz Burgmann, Alexandra Maier-Salamon, S G Wicha, W Jäger, M Zeitlinger, T Stimpfl, T Wittek, F Thalhammer
Published 2021-06-01

The Use of Translational Modelling and Simulation to Develop Immunomodulatory Therapy as an Adjunct to Antibiotic Treatment in the Context of Pneumonia

by Robin Michelet, Moreno Ursino, Sandrine Boulet, Sebastian Franck, Fiordiligie Casilag, Mara Baldry, Jens Rolff, Madelé van Dyk, Sebastian G. Wicha, Jean-Claude Sirard, Emmanuelle Comets, Sarah Zohar, Charlotte Kloft
Published 2021-04-01

Saliva for Precision Dosing of Antifungal Drugs: Saliva Population PK Model for Voriconazole Based on a Systematic Review.

by Hannah Yejin Kim, Hannah Yejin Kim, Hannah Yejin Kim, Anne-Grete Märtson, Erwin Dreesen, Isabel Spriet, Isabel Spriet, Sebastian G. Wicha, Andrew J. McLachlan, Jan-Willem Alffenaar, Jan-Willem Alffenaar, Jan-Willem Alffenaar
Published 2020-06-01