A novel framework for integrating a priori domain knowledge into traditional data analysis in the context of bioinformatics

by Denaxas, Spiridon Christoforos
Published 2008

Treating heterogeneity and uncertainty in data integration: study on Brazilian healthcare databases.

by Marcos Barreto, Spiros Denaxas
Published 2017-04-01

Low-density lipoprotein cholesterol and atrial fibrillation; A Mendelian randomization study using UK-Biobank data

by Michail Katsoulis, Spiros Denaxas, Riyaz Patel, Harry Hemingway
Published 2017-04-01

Natural language processing for disease phenotyping in UK primary care records for research: a pilot study in myocardial infarction and death

by Anoop D. Shah, Emily Bailey, Tim Williams, Spiros Denaxas, Richard Dobson, Harry Hemingway
Published 2019-11-01

Identifying clinically important COPD sub-types using data-driven approaches in primary care population based electronic health records

by Maria Pikoula, Jennifer Kathleen Quint, Francis Nissen, Harry Hemingway, Liam Smeeth, Spiros Denaxas
Published 2019-04-01

Machine learning models in electronic health records can outperform conventional survival models for predicting patient mortality in coronary artery disease.

by Andrew J Steele, Spiros C Denaxas, Anoop D Shah, Harry Hemingway, Nicholas M Luscombe
Published 2018-01-01

Temporal trends in heart failure medication prescription in a population-based cohort study

by Ilonca Vaartjes, Anoop Shah, S Denaxas, J Cleland, Alicia Uijl, Diederick Grobbee, Arno Hoes, Stefan Koudstaal
Published 2021-03-01

Extracting diagnoses and investigation results from unstructured text in electronic health records by semi-supervised machine learning.

by Zhuoran Wang, Anoop D Shah, A Rosemary Tate, Spiros Denaxas, John Shawe-Taylor, Harry Hemingway
Published 2012-01-01

Methods for enhancing the reproducibility of clinical epidemiology research in linked electronic health records: results and lessons learned from the CALIBER platform

by Spiros Denaxas, Holger Kunz, Liam Smeeth, Arturo Gonzalez-Izquierdo, Harry Boutselakis, Maria Pikoula, Harry Hemingway
Published 2017-04-01

Using nationwide ‘big data’ from linked electronic health records to help improve outcomes in cardiovascular diseases: 33 studies using methods from epidemiology, informatics, econ...

by Harry Hemingway, Gene S Feder, Natalie K Fitzpatrick, Spiros Denaxas, Anoop D Shah, Adam D Timmis
Published 2017-01-01

Healthcare use by people who use illicit opioids (HUPIO): development of a cohort based on electronic primary care records in England [version 2; peer review: 2 approved]

by Dan Lewer, Prianka Padmanathan, Muhammad Qummer ul Arfeen, Spiros Denaxas, Harriet Forbes, Arturo Gonzalez-Izquierdo, Matt Hickman
Published 2021-05-01

Healthcare use by people who use illicit opioids (HUPIO): development of a cohort based on electronic primary care records in England [version 1; peer review: 2 approved]

by Dan Lewer, Prianka Padmanathan, Muhammed Qummer ul Arfeen, Spiros Denaxas, Harriet Forbes, Arturo Gonzalez-Izquierdo, Matt Hickman
Published 2020-12-01

Methods for enhancing the reproducibility of biomedical research findings using electronic health records

by Spiros Denaxas, Kenan Direk, Arturo Gonzalez-Izquierdo, Maria Pikoula, Aylin Cakiroglu, Jason Moore, Harry Hemingway, Liam Smeeth
Published 2017-09-01

Metformin use and cardiovascular outcomes after acute myocardial infarction in patients with type 2 diabetes: a cohort study

by Daniel I. Bromage, Tom R. Godec, Mar Pujades-Rodriguez, Arturo Gonzalez-Izquierdo, S. Denaxas, Harry Hemingway, Derek M. Yellon
Published 2019-12-01

Identification and validation of myocardial infarction and stroke outcomes at scale in UK Biobank

by Christian Schnier, Spiros Denaxas, Rosalind Eggo, Riyaz Patel, Qiuli Zhang, Rebecca Woodfield, Robin Flaig, Harry Hemingway, Cathie Sudlow
Published 2017-04-01

Ethnicity and the first diagnosis of a wide range of cardiovascular diseases: Associations in a linked electronic health record cohort of 1 million patients.

by Julie George, Rohini Mathur, Anoop Dinesh Shah, Mar Pujades-Rodriguez, Spiros Denaxas, Liam Smeeth, Adam Timmis, Harry Hemingway
Published 2017-01-01

Socioeconomic deprivation and the incidence of 12 cardiovascular diseases in 1.9 million women and men: implications for risk prediction and prevention.

by Mar Pujades-Rodriguez, Adam Timmis, Dimitris Stogiannis, Eleni Rapsomaniki, Spiros Denaxas, Anoop Shah, Gene Feder, Mika Kivimaki, Harry Hemingway
Published 2014-01-01

Hospital bed capacity and usage across secondary healthcare providers in England during the first wave of the COVID-19 pandemic: a descriptive analysis

by Sebastian Vollmer, John M Dennis, Spiros Denaxas, Andrew McGovern, Nick Thomas, Bilal Akhter Mateen, Harrison Wilde, Andrew Duncan, Matt Keeling
Published 2021-01-01

Impact of baseline cases of cough and fever on UK COVID-19 diagnostic testing rates: estimates from the Bug Watch community cohort study [version 2; peer review: 2 approved]

by Max T. Eyre, Rachel Burns, Victoria Kirkby, Catherine Smith, Spiros Denaxas, Vincent Nguyen, Andrew Hayward, Laura Shallcross, Ellen Fragaszy, Robert W. Aldridge
Published 2021-01-01

Time spent at blood pressure target and the risk of death and cardiovascular diseases.

by Sheng-Chia Chung, Mar Pujades-Rodriguez, Bram Duyx, Spiros C Denaxas, Laura Pasea, Aroon Hingorani, Adam Timmis, Bryan Williams, Harry Hemingway
Published 2018-01-01