Selective activation of vitamin D receptor by lithocholic acid acetate, a bile acid derivative

by Ryutaro Adachi, Yoshio Honma, Hiroyuki Masuno, Katsuyoshi Kawana, Iichiro Shimomura, Sachiko Yamada, Makoto Makishima
Published 2005-01-01

Inhibition of MGAT2 modulates fat‐induced gut peptide release and fat intake in normal mice and ameliorates obesity and diabetes in ob/ob mice fed on a high‐fat diet

by Taisuke Mochida, Kazumi Take, Toshiyuki Maki, Masanori Nakakariya, Ryutaro Adachi, Kenjiro Sato, Tomoyuki Kitazaki, Shiro Takekawa
Published 2020-03-01

Lithocholic acid derivatives act as selective vitamin D receptor modulators without inducing hypercalcemia

by Michiyasu Ishizawa, Manabu Matsunawa, Ryutaro Adachi, Shigeyuki Uno, Kazumasa Ikeda, Hiroyuki Masuno, Masato Shimizu, Ken-ichi Iwasaki, Sachiko Yamada, Makoto Makishima
Published 2008-04-01

Pharmacological Inhibition of Monoacylglycerol O-Acyltransferase 2 Improves Hyperlipidemia, Obesity, and Diabetes by Change in Intestinal Fat Utilization.

by Kazumi Take, Taisuke Mochida, Toshiyuki Maki, Yoshinori Satomi, Megumi Hirayama, Masanori Nakakariya, Nobuyuki Amano, Ryutaro Adachi, Kenjiro Sato, Tomoyuki Kitazaki, Shiro Takekawa
Published 2016-01-01

Discovery and pharmacological characterization of a new class of prolyl-tRNA synthetase inhibitor for anti-fibrosis therapy.

by Akira Shibata, Masako Kuno, Ryutaro Adachi, Yosuke Sato, Harumi Hattori, Atsushi Matsuda, Yuumi Okuzono, Keiko Igaki, Yusuke Tominari, Terufumi Takagi, Masato Yabuki, Masanori Okaniwa
Published 2017-01-01