Principles of Effective and Robust Innate Immune Response to Viral Infections: A Multiplex Network Analysis

by Yufan Huang, Huaiyu Dai, Ruian Ke, Ruian Ke
Published 2019-07-01

Evolutionary analysis of human immunodeficiency virus type 1 therapies based on conditionally replicating vectors.

by Ruian Ke, James O Lloyd-Smith
Published 2012-01-01

An integrative model of ion regulation in yeast.

by Ruian Ke, Piers J Ingram, Ken Haynes
Published 2013-01-01

Change in global transmission rates of COVID-19 through May 6 2020.

by Ethan Obie Romero-Severson, Nick Hengartner, Grant Meadors, Ruian Ke
Published 2020-01-01

Causes and Consequences of Spatial Within-Host Viral Spread

by Molly E. Gallagher, Christopher B. Brooke, Ruian Ke, Katia Koelle
Published 2018-11-01

Modeling the Effects of Vorinostat In Vivo Reveals both Transient and Delayed HIV Transcriptional Activation and Minimal Killing of Latently Infected Cells.

by Ruian Ke, Sharon R Lewin, Julian H Elliott, Alan S Perelson
Published 2015-10-01

Phylodynamic analysis of the emergence and epidemiological impact of transmissible defective dengue viruses.

by Ruian Ke, John Aaskov, Edward C Holmes, James O Lloyd-Smith
Published 2013-02-01

Rational Design and Adaptive Management of Combination Therapies for Hepatitis C Virus Infection.

by Ruian Ke, Claude Loverdo, Hangfei Qi, Ren Sun, James O Lloyd-Smith
Published 2015-06-01

High Contagiousness and Rapid Spread of Severe Acute Respiratory Syndrome Coronavirus 2

by Steven Sanche, Yen Ting Lin, Chonggang Xu, Ethan Romero-Severson, Nick Hengartner, Ruian Ke
Published 2020-07-01

Single cell heterogeneity in influenza A virus gene expression shapes the innate antiviral response to infection.

by Jiayi Sun, J Cristobal Vera, Jenny Drnevich, Yen Ting Lin, Ruian Ke, Christopher B Brooke
Published 2020-07-01

NS5A inhibitors unmask differences in functional replicase complex half-life between different hepatitis C virus strains.

by Tiffany Benzine, Ryan Brandt, William C Lovell, Daisuke Yamane, Petra Neddermann, Raffaele De Francesco, Stanley M Lemon, Alan S Perelson, Ruian Ke, David R McGivern
Published 2017-06-01

Timing of Antiviral Treatment Initiation is Critical to Reduce SARS‐CoV‐2 Viral Load

by Antonio Gonçalves, Julie Bertrand, Ruian Ke, Emmanuelle Comets, Xavier deLamballerie, Denis Malvy, Andrés Pizzorno, Olivier Terrier, Manuel Rosa Calatrava, France Mentré, Patrick Smith, Alan S. Perelson, Jérémie Guedj
Published 2020-09-01

A quantitative model used to compare within-host SARS-CoV-2, MERS-CoV, and SARS-CoV dynamics provides insights into the pathogenesis and treatment of SARS-CoV-2.

by Kwang Su Kim, Keisuke Ejima, Shoya Iwanami, Yasuhisa Fujita, Hirofumi Ohashi, Yoshiki Koizumi, Yusuke Asai, Shinji Nakaoka, Koichi Watashi, Kazuyuki Aihara, Robin N Thompson, Ruian Ke, Alan S Perelson, Shingo Iwami
Published 2021-03-01

A quantitative high-resolution genetic profile rapidly identifies sequence determinants of hepatitis C viral fitness and drug sensitivity.

by Hangfei Qi, C Anders Olson, Nicholas C Wu, Ruian Ke, Claude Loverdo, Virginia Chu, Shawna Truong, Roland Remenyi, Zugen Chen, Yushen Du, Sheng-Yao Su, Laith Q Al-Mawsawi, Ting-Ting Wu, Shu-Hua Chen, Chung-Yen Lin, Weidong Zhong, James O Lloyd-Smith, Ren Sun
Published 2014-04-01