Editorial: Clearance Pathways for Amyloid-β. Significance for Alzheimer's Disease and Its Therapy

by Roxana O. Carare
Published 2017-10-01

Dispersion in porous media in oscillatory flow between flat plates: applications to intrathecal, periarterial and paraarterial solute transport in the central nervous system

by M. Keith Sharp, Roxana O. Carare, Bryn A. Martin
Published 2019-05-01

Vital Functions Contribute to the Spread of Extracellular Fluids in the Brain: Comparison Between Life and Death

by Alina Piotrowska, Karsten Winter, Roxana O. Carare, Ingo Bechmann
Published 2020-02-01

3D Reconstruction of the Neurovascular Unit Reveals Differential Loss of Cholinergic Innervation in the Cortex and Hippocampus of the Adult Mouse Brain

by Shereen Nizari, Roxana O. Carare, Ignacio A. Romero, Cheryl A. Hawkes
Published 2019-07-01

A control mechanism for intra-mural peri-arterial drainage via astrocytes: How neuronal activity could improve waste clearance from the brain.

by Alexandra K Diem, Roxana O Carare, Roy O Weller, Neil W Bressloff
Published 2018-01-01

Cerebrovascular Smooth Muscle Cells as the Drivers of Intramural Periarterial Drainage of the Brain

by Roxana Aldea, Roy O. Weller, Donna M. Wilcock, Roxana O. Carare, Giles Richardson
Published 2019-01-01

Loss of cholinergic innervation differentially affects eNOS-mediated blood flow, drainage of Aβ and cerebral amyloid angiopathy in the cortex and hippocampus of adult mice

by Shereen Nizari, Jack A. Wells, Roxana O. Carare, Ignacio A. Romero, Cheryl A. Hawkes
Published 2021-01-01

A Simulation Model of Periarterial Clearance of Amyloid-beta from the Brain

by Alexandra Katharina Diem, Alexandra Katharina Diem, Mingyi eTan, Neil W. Bressloff, Cheryl eHawkes, Alan W. J. Morris, Alan W. J. Morris, Roy O. Weller, Roxana O. Carare, Roxana O. Carare
Published 2016-02-01

Solving an Old Dogma: Is it an Arteriole or a Venule?

by Matthew MacGregor Sharp, Theodore P. Criswell, Howard Dobson, Ciara Finucane, Ajay Verma, Roxana O. Carare
Published 2019-10-01

The cerebrovascular basement membrane: role in the clearance of β-amyloid and cerebral amyloid angiopathy

by Alan W. J. Morris, Roxana O. Carare, Stefanie eSchreiber, Stefanie eSchreiber, Cheryl A. Hawkes
Published 2014-09-01

Arterial Pulsations cannot Drive Intramural Periarterial Drainage: Significance for Aβ Drainage

by Alexandra K. Diem, Matthew MacGregor Sharp, Maureen Gatherer, Neil W. Bressloff, Roxana O. Carare, Giles Richardson
Published 2017-08-01

Amyloid-β and α-Synuclein Immunotherapy: From Experimental Studies to Clinical Trials

by Jacqui Taryn Nimmo, Louise Kelly, Ajay Verma, Roxana O. Carare, James A. R. Nicoll, Jean-Cosme Dodart
Published 2021-09-01

Disruption of arterial perivascular drainage of amyloid-β from the brains of mice expressing the human APOE ε4 allele.

by Cheryl A Hawkes, Patrick M Sullivan, Sarah Hands, Roy O Weller, James A R Nicoll, Roxana O Carare
Published 2012-01-01

Quantitative proteomic profiling of white matter in cases of cerebral amyloid angiopathy reveals upregulation of extracellular matrix proteins and clusterin

by Antigoni Manousopoulou, Ho Ming Yuen, Matt MacGregor Sharp, Satoshi Saito, Roxana Aldea, Norman Mazer, Spiros D Garbis, Roxana O Carare
Published 2020-10-01

Novel antibodies detect additional α-synuclein pathology in synucleinopathies: potential development for immunotherapy

by Jacqui T. Nimmo, Ajay Verma, Jean-Cosme Dodart, Chang Yi Wang, Jimmy Savistchenko, Ronald Melki, Roxana O. Carare, James A. R. Nicoll
Published 2020-11-01

Peri‐arterial pathways for clearance of α‐Synuclein and tau from the brain: Implications for the pathogenesis of dementias and for immunotherapy

by Jacqui Nimmo, David A. Johnston, J. C. Dodart, Matthew T. MacGregor‐Sharp, Roy O. Weller, James A. R. Nicoll, Ajay Verma, Roxana O. Carare
Published 2020-01-01

Hypercholesterolemia induced cerebral small vessel disease.

by Peter Kraft, Michael K Schuhmann, Cornelia Garz, Solveig Jandke, Daniela Urlaub, Stine Mencl, Alma Zernecke, Hans-Jochen Heinze, Roxana O Carare, Christoph Kleinschnitz, Stefanie Schreiber
Published 2017-01-01

Demonstrating a reduced capacity for removal of fluid from cerebral white matter and hypoxia in areas of white matter hyperintensity associated with age and dementia

by Matthew MacGregor Sharp, Satoshi Saito, Abby Keable, Maureen Gatherer, Roxana Aldea, Nivedita Agarwal, Julie E. Simpson, Stephen B. Wharton, Roy O. Weller, Roxana O. Carare
Published 2020-08-01

Vascular α1A Adrenergic Receptors as a Potential Therapeutic Target for IPAD in Alzheimer’s Disease

by Miles Frost, Abby Keable, Dan Baseley, Amber Sealy, Diana Andreea Zbarcea, Maureen Gatherer, Ho Ming Yuen, Matt MacGregor Sharp, Roy O. Weller, Johannes Attems, Colin Smith, Paul R. Chiarot, Roxana O. Carare
Published 2020-09-01

The Pattern of AQP4 Expression in the Ageing Human Brain and in Cerebral Amyloid Angiopathy

by Raisah Owasil, Ronan O’Neill, Abby Keable, Jacqui Nimmo, Matthew MacGregor Sharp, Louise Kelly, Satoshi Saito, Julie E. Simpson, Roy O. Weller, Colin Smith, Johannes Attems, Stephen B. Wharton, Ho Ming Yuen, Roxana O. Carare
Published 2020-02-01