Irinotecan Induces Disease Remission in Xenograft Mouse Models of Pediatric <i>MLL</i>-Rearranged Acute Lymphoblastic Leukemia

by Mark Kerstjens, Patricia Garrido Castro, Sandra S. Pinhanços, Pauline Schneider, Priscilla Wander, Rob Pieters, Ronald W. Stam
Published 2021-06-01

Identification of genes transcriptionally responsive to the loss of MLL fusions in MLL-rearranged acute lymphoblastic leukemia.

by Marieke H van der Linden, Lidija Seslija, Pauline Schneider, Emma M C Driessen, Patricia Garrido Castro, Dominique J P M Stumpel, Eddy van Roon, Jasper de Boer, Owen Williams, Rob Pieters, Ronald W Stam
Published 2015-01-01

Preclinical Evaluation of Carfilzomib for Infant KMT2A-Rearranged Acute Lymphoblastic Leukemia

by Laurence C. Cheung, Laurence C. Cheung, Rebecca de Kraa, Joyce Oommen, Grace-Alyssa Chua, Sajla Singh, Anastasia M. Hughes, Emanuela Ferrari, Jette Ford, Sung K. Chiu, Ronald W. Stam, Ursula R. Kees, Sébastien Malinge, Rishi S. Kotecha, Rishi S. Kotecha, Rishi S. Kotecha
Published 2021-04-01

Partner independent fusion gene detection by multiplexed CRISPR-Cas9 enrichment and long read nanopore sequencing

by Christina Stangl, Sam de Blank, Ivo Renkens, Liset Westera, Tamara Verbeek, Jose Espejo Valle-Inclan, Rocio Chamorro González, Anton G. Henssen, Markus J. van Roosmalen, Ronald W. Stam, Emile E. Voest, Wigard P. Kloosterman, Gijs van Haaften, Glen R. Monroe
Published 2020-06-01

High-throughput drug screening reveals Pyrvinium pamoate as effective candidate against pediatric MLL-rearranged acute myeloid leukemia

by Priscilla Wander, Susan T.C.J.M. Arentsen-Peters, Sandra S. Pinhanҫos, Bianca Koopmans, M.Emmy M. Dolman, Rijndert Ariese, Frank L. Bos, Patricia Garrido Castro, Luke Jones, Pauline Schneider, Miriam Guillen Navarro, Jan J. Molenaar, Anne C. Rios, C. Michel Zwaan, Ronald W. Stam
Published 2021-05-01

Development Refractoriness of MLL-Rearranged Human B Cell Acute Leukemias to Reprogramming into Pluripotency

by Alvaro Muñoz-López, Damià Romero-Moya, Cristina Prieto, Verónica Ramos-Mejía, Antonio Agraz-Doblas, Ignacio Varela, Marcus Buschbeck, Anna Palau, Xonia Carvajal-Vergara, Alessandra Giorgetti, Anthony Ford, Majlinda Lako, Isabel Granada, Neus Ruiz-Xivillé, Sandra Rodríguez-Perales, Raul Torres-Ruíz, Ronald W. Stam, Jose Luis Fuster, Mario F. Fraga, Mahito Nakanishi, Gianni Cazzaniga, Michela Bardini, Isabel Cobo, Gustavo F. Bayon, Agustin F. Fernandez, Clara Bueno, Pablo Menendez
Published 2016-10-01