New Markers in Monitoring the Reactivation of Hepatitis B Virus Infection in Immunocompromised Hosts

by Valentina Svicher, Romina Salpini, Vincenzo Malagnino, Lorenzo Piermatteo, Mohammad Alkhatib, Carlotta Cerva, Loredana Sarmati
Published 2019-08-01

Hepatitis B virus reactivation sustained by a hepatitis B virus surface antigen immune-escape mutant isolate in a patient who was hepatitis B core antibody positive during treatmen...

by Luca Foroghi Biland, Ludovica Ferrari, Vincenzo Malagnino, Elisabetta Teti, Carlotta Cerva, Adele Gentile, Marianna Aragri, Romina Salpini, Valentina Svicher, Massimo Andreoni, Loredana Sarmati
Published 2019-09-01

Different Patterns of HIV-1 Replication in MACROPHAGES is Led by Co-Receptor Usage

by Ana Borrajo, Alessandro Ranazzi, Michela Pollicita, Maria Concetta Bellocchi, Romina Salpini, Maria Vittoria Mauro, Francesca Ceccherini-Silberstein, Carlo Federico Perno, Valentina Svicher, Stefano Aquaro
Published 2019-06-01

Poor CD4/CD8 ratio recovery in HBcAb-positive HIV patients with worse immune status is associated with significantly higher CD8 cell numbers

by Vincenzo Malagnino, Carlotta Cerva, Elisabetta Teti, Laura Campogiani, Mirko Compagno, Luca Foroghi Biland, Laura Saderi, Daniele Armenia, Romina Salpini, Valentina Svicher, Giovanni Sotgiu, Marco Iannetta, Massimo Andreoni, Loredana Sarmati
Published 2021-02-01

High rates of chronic HBV genotype E infection in a group of migrants in Italy from West Africa: Virological characteristics associated with poor immune clearance.

by Vincenzo Malagnino, Romina Salpini, Gaetano Maffongelli, Arianna Battisti, Lavinia Fabeni, Lorenzo Piermatteo, Luna Colagrossi, Vanessa Fini, Alessandra Ricciardi, Cesare Sarrecchia, Carlo Federico Perno, Massimo Andreoni, Valentina Svicher, Loredana Sarmati
Published 2018-01-01

An Increase in the Levels of Middle Surface Antigen Characterizes Patients Developing HBV-Driven Liver Cancer Despite Prolonged Virological Suppression

by Giuseppina Brancaccio, Romina Salpini, Lorenzo Piermatteo, Matteo Surdo, Vanessa Fini, Luna Colagrossi, Marco Cantone, Arianna Battisti, Yasunori Oda, Domenico Di Carlo, Francesca Ceccherini-Silberstein, Carlo Federico Perno, Giovanni Battista Gaeta, Valentina Svicher
Published 2021-04-01

HBcAb Positivity Is a Risk Factor for an Increased Detectability of HIV RNA After Switching to a Two-Drug Regimen Lamivudine-Based (2DR-3TC-Based) Treatment: Analysis of a Multicen...

by Vincenzo Malagnino, Elisabetta Teti, Mirko Compagno, Luigi Coppola, Romina Salpini, Valentina Svicher, Monica Basso, Giuliana Battagin, Sandro Panese, Maria Cristina Rossi, Renzo Scaggiante, Daniela Zago, Marco Iannetta, Saverio Giuseppe Parisi, Massimo Andreoni, Loredana Sarmati
Published 2021-02-01

Long-Term SARS-CoV-2 Infection Associated with Viral Dissemination in Different Body Fluids Including Bile in Two Patients with Acute Cholecystitis

by Rossana Scutari, Lorenzo Piermatteo, Matteo Ciancio Manuelli, Marco Iannetta, Romina Salpini, Ada Bertoli, Claudia Alteri, Patrizia Saccomandi, Maria Concetta Bellocchi, Vincenzo Malagnino, Elisabetta Teti, Daniele Sforza, Leandro Siragusa, Michele Grande, Loredana Sarmati, Valentina Svicher, Massimo Andreoni, Francesca Ceccherini-Silberstein
Published 2020-11-01

HIV-1 drug resistance testing is essential for heavily-treated patients switching from first- to second-line regimens in resource-limited settings: evidence from routine clinical p...

by Desire Takou, Joseph Fokam, Georges Teto, Maria-Mercedes Santoro, Francesca Ceccherini-Silberstein, Aubin Joseph Nanfack, Samuel Martin Sosso, Béatrice Dambaya, Romina Salpini, Serge Clotaire Billong, Caterina Gori, Charles Ntungwen Fokunang, Giulia Cappelli, Vittorio Colizzi, Carlo-Federico Perno, Alexis Ndjolo
Published 2019-03-01

HCV genotypes are differently prone to the development of resistance to linear and macrocyclic protease inhibitors.

by Valeria Cento, Carmen Mirabelli, Romina Salpini, Salvatore Dimonte, Anna Artese, Giosuè Costa, Fabio Mercurio, Valentina Svicher, Lucia Parrotta, Ada Bertoli, Marco Ciotti, Daniele Di Paolo, Cesare Sarrecchia, Massimo Andreoni, Stefano Alcaro, Mario Angelico, Carlo Federico Perno, Francesca Ceccherini-Silberstein
Published 2012-01-01

Cryptic HBV Replicative Activity Is Frequently Revealed in Anti-HBc-Positive/HBsAg-Negative Patients with HIV Infection by Highly Sensitive Molecular Assays, and Can Be Predicted b...

by Romina Salpini, Vincenzo Malagnino, Lorenzo Piermatteo, Tiziana Mulas, Mohammad Alkhatib, Rossana Scutari, Elisabetta Teti, Carlotta Cerva, Katia Yu La Yu La Rosa, Marta Brugneti, Ada Bertoli, Benedetta Rossi, Vera Holzmayer, Jeffrey Gersch, Mary Kuhns, Gavin Cloherty, Francesca Ceccherini-Silberstein, Carlo-Federico Perno, Marco Iannetta, Massimo Andreoni, Loredana Sarmati, Valentina Svicher
Published 2020-11-01

A Hyper-Glycosylation of HBV Surface Antigen Correlates with HBsAg-Negativity at Immunosuppression-Driven HBV Reactivation in Vivo and Hinders HBsAg Recognition In Vitro

by Romina Salpini, Lorenzo Piermatteo, Arianna Battisti, Luna Colagrossi, Marianna Aragri, Katia Yu La Rosa, Ada Bertoli, Patrizia Saccomandi, Miriam Lichtner, Massimo Marignani, Sarah Maylin, Constance Delaugerre, Filomena Morisco, Nicola Coppola, Aldo Marrone, Nerio Iapadre, Carlotta Cerva, Stefano Aquaro, Mario Angelico, Loredana Sarmati, Massimo Andreoni, Jens Verheyen, Francesca Ceccherini-Silberstein, Massimo Levrero, Carlo Federico Perno, Laura Belloni, Valentina Svicher
Published 2020-02-01

HDV Can Constrain HBV Genetic Evolution in HBsAg: Implications for the Identification of Innovative Pharmacological Targets

by Luna Colagrossi, Romina Salpini, Rossana Scutari, Luca Carioti, Arianna Battisti, Lorenzo Piermatteo, Ada Bertoli, Lavinia Fabeni, Carmine Minichini, Pascale Trimoulet, Hervé Fleury, Elena Nebuloso, Maria De Cristofaro, Giuseppina Cappiello, Alberto Spanò, Vincenzo Malagnino, Terenzio Mari, Angelo Barlattani, Nerio Iapadre, Miriam Lichtner, Claudio Mastroianni, Ilaria Lenci, Caterina Pasquazzi, Giuseppe Maria De Sanctis, Alfonso Galeota Lanza, Maria Stanzione, Gianfranca Stornaiuolo, Massimo Marignani, Loredana Sarmati, Massimo Andreoni, Mario Angelico, Francesca Ceccherini-Silberstein, Carlo-Federico Perno, Nicola Coppola, Valentina Svicher
Published 2018-07-01

Genetic Determinants in a Critical Domain of NS5A Correlate with Hepatocellular Carcinoma in Cirrhotic Patients Infected with HCV Genotype 1b

by Mohammad Alkhatib, Velia Chiara Di Maio, Valentina De Murtas, Ennio Polilli, Martina Milana, Elisabetta Teti, Gianluca Fiorentino, Vincenza Calvaruso, Silvia Barbaliscia, Ada Bertoli, Rossana Scutari, Luca Carioti, Valeria Cento, Maria Mercedes Santoro, Alessandro Orro, Ivana Maida, Ilaria Lenci, Loredana Sarmati, Antonio Craxì, Caterina Pasquazzi, Giustino Parruti, Sergio Babudieri, Luciano Milanesi, Massimo Andreoni, Mario Angelico, Carlo Federico Perno, Francesca Ceccherini-Silberstein, Valentina Svicher, Romina Salpini, on behalf of HIRMA (Hepatocarcinoma Innovative Research MArkers) and Fondazione Vironet C (HCV Virology Italian Resistance
Published 2021-04-01

Immune-escape mutations and stop-codons in HBsAg develop in a large proportion of patients with chronic HBV infection exposed to anti-HBV drugs in Europe

by Luna Colagrossi, Lucas E. Hermans, Romina Salpini, Domenico Di Carlo, Suzan D. Pas, Marta Alvarez, Ziv Ben-Ari, Greet Boland, Bianca Bruzzone, Nicola Coppola, Carole Seguin-Devaux, Tomasz Dyda, Federico Garcia, Rolf Kaiser, Sukran Köse, Henrik Krarup, Ivana Lazarevic, Maja M. Lunar, Sarah Maylin, Valeria Micheli, Orna Mor, Simona Paraschiv, Dimitros Paraskevis, Mario Poljak, Elisabeth Puchhammer-Stöckl, François Simon, Maja Stanojevic, Kathrine Stene-Johansen, Nijaz Tihic, Pascale Trimoulet, Jens Verheyen, Adriana Vince, Snjezana Zidovec Lepej, Nina Weis, Tülay Yalcinkaya, Charles A. B. Boucher, Annemarie M. J. Wensing, Carlo F. Perno, Valentina Svicher, on behalf of the HEPVIR working group of the European Society for translational antiviral research (ESAR)
Published 2018-06-01