Radiation synergizes with antitumor activity of CD13-targeted tissue factor in a HT1080 xenograft model of human soft tissue sarcoma.

by Caroline Brand, Burkhard Greve, Tobias Bölling, Hans T Eich, Normann Willich, Saliha Harrach, Heike Hintelmann, Georg Lenz, Rolf M Mesters, Torsten Kessler, Christoph Schliemann, Wolfgang E Berdel, Christian Schwöppe
Published 2020-01-01

Targeting Tissue Factor to Tumor Vasculature to Induce Tumor Infarction

by Andrew F. Berdel, Christian Schwöppe, Caroline Brand, Saliha Harrach, Kathrin Brömmel, Heike Hintelmann, Georg Lenz, Ruediger Liersch, Hauke Heinzow, Christoph Schliemann, Rolf M. Mesters, Wolfgang E. Berdel, Torsten Kessler
Published 2021-06-01

Aminopeptidase N (CD13): Expression, Prognostic Impact, and Use as Therapeutic Target for Tissue Factor Induced Tumor Vascular Infarction in Soft Tissue Sarcoma

by Torsten Kessler, Ariane Baumeier, Caroline Brand, Michael Grau, Linus Angenendt, Saliha Harrach, Ursula Stalmann, Lars Henning Schmidt, Georg Gosheger, Jendrik Hardes, Dimosthenis Andreou, Johannes Dreischalück, Georg Lenz, Eva Wardelmann, Rolf M. Mesters, Christian Schwöppe, Wolfgang E. Berdel, Wolfgang Hartmann, Christoph Schliemann
Published 2018-12-01

First-In-Class CD13-Targeted Tissue Factor tTF-NGR in Patients with Recurrent or Refractory Malignant Tumors: Results of a Phase I Dose-Escalation Study

by Christoph Schliemann, Mirjam Gerwing, Hauke Heinzow, Saliha Harrach, Christian Schwöppe, Moritz Wildgruber, Anna A. Hansmeier, Linus Angenendt, Andrew F. Berdel, Ursula Stalmann, Björna Berning, Karsten Kratz-Albers, Kristina Middelberg-Bisping, Stefanie Wiebe, Jörn Albring, Christian Wilms, Wolfgang Hartmann, Eva Wardelmann, Tobias Krähling, Walter Heindel, Joachim Gerss, Eike Bormann, Hartmut Schmidt, Georg Lenz, Torsten Kessler, Rolf M. Mesters, Wolfgang E. Berdel
Published 2020-06-01