Effects of the adiponectin mimetic compound ALY688 on glucose and fat metabolism in visceral and subcutaneous rat adipocytes

by Daniel Da Eira, Shailee Jani, Hyekyoung Sung, Gary Sweeney, Rolando B. Ceddia
Published 2020-01-01

Loss of the anorexic response to systemic 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside administration despite reducing hypothalamic AMP-activated protein kinase phosphorylat...

by Kaio F Vitzel, George Bikopoulos, Steven Hung, Rui Curi, Rolando B Ceddia
Published 2013-01-01

Chronic AMP-kinase activation with AICAR reduces adiposity by remodeling adipocyte metabolism and increasing leptin sensitivity

by Mandeep P. Gaidhu, Andrea Frontini, Steven Hung, Kathryn Pistor, Saverio Cinti, Rolando B. Ceddia
Published 2011-09-01

Chronic treatment with the AMP-kinase activator AICAR increases glycogen storage and fatty acid oxidation in skeletal muscles but does not reduce hyperglucagonemia and hyperglycemi...

by Kaio F Vitzel, George Bikopoulos, Steven Hung, Kathryn E Pistor, Jessica D Patterson, Rui Curi, Rolando B Ceddia
Published 2013-01-01

Distinct mechanisms involving diacylglycerol, ceramides, and inflammation underlie insulin resistance in oxidative and glycolytic muscles from high fat-fed rats

by Shailee Jani, Daniel Da Eira, Ishvinder Hadday, George Bikopoulos, Arta Mohasses, Ricardo A. de Pinho, Rolando B. Ceddia
Published 2021-09-01

Prolonged AICAR-induced AMP-kinase activation promotes energy dissipation in white adipocytes: novel mechanisms integrating HSL and ATGL

by Mandeep P. Gaidhu, Sergiu Fediuc, Nicole M. Anthony, Mandy So, Mani Mirpourian, Robert L.S. Perry, Rolando B. Ceddia
Published 2009-04-01

Muscle-specific adaptations, impaired oxidative capacity and maintenance of contractile function characterize diet-induced obese mouse skeletal muscle.

by Karin E Shortreed, Matthew P Krause, Julianna H Huang, Dili Dhanani, Jasmin Moradi, Rolando B Ceddia, Thomas J Hawke
Published 2009-10-01

Enhanced lipid oxidation and maintenance of muscle insulin sensitivity despite glucose intolerance in a diet-induced obesity mouse model.

by Karin E Trajcevski, Hayley M O'Neill, David C Wang, Melissa M Thomas, Dhuha Al-Sajee, Gregory R Steinberg, Rolando B Ceddia, Thomas J Hawke
Published 2013-01-01

Endothelial-specific FoxO1 depletion prevents obesity-related disorders by increasing vascular metabolism and growth

by Martina Rudnicki, Ghoncheh Abdifarkosh, Emmanuel Nwadozi, Sofhia V Ramos, Armin Makki, Diane M Sepa-Kishi, Rolando B Ceddia, Christopher GR Perry, Emilie Roudier, Tara L Haas
Published 2018-12-01

Resistance Exercise Modulates Oxidative Stress Parameters and TNF-α Content in the Heart of Mice with Diet-Induced Obesity

by Pauline Souza Effting, Stella M. S. Brescianini, Helen R. Sorato, Bruna Barros Fernandes, Giulia dos S. Pedroso Fidelis, Paulo Roberto L. da Silva, Paulo César L. Silveira, Renata T. Nesi, Rolando B. Ceddia, Ricardo A. Pinho
Published 2019-04-01