Nasal Immunization with the C-Terminal Domain of Bcla3 Induced Specific IgG Production and Attenuated Disease Symptoms in Mice Infected with <i>Clostridioides difficile</i> Spores

by Ana Raquel Maia, Rodrigo Reyes-Ramírez, Marjorie Pizarro-Guajardo, Anella Saggese, Ezio Ricca, Loredana Baccigalupi, Daniel Paredes-Sabja
Published 2020-09-01

Induction of a Specific Humoral Immune Response by Nasal Delivery of Bcla2_ctd of <i>Clostridioides difficile</i>

by Ana Raquel Maia, Rodrigo Reyes-Ramírez, Marjorie Pizarro-Guajardo, Anella Saggese, Pablo Castro-Córdova, Rachele Isticato, Ezio Ricca, Daniel Paredes-Sabja, Loredana Baccigalupi
Published 2020-02-01

Clostridium difficile exosporium cysteine-rich proteins are essential for the morphogenesis of the exosporium layer, spore resistance, and affect C. difficile pathogenesis.

by Paulina Calderón-Romero, Pablo Castro-Córdova, Rodrigo Reyes-Ramírez, Mauro Milano-Céspedes, Enzo Guerrero-Araya, Marjorie Pizarro-Guajardo, Valeria Olguín-Araneda, Fernando Gil, Daniel Paredes-Sabja
Published 2018-08-01

Entry of spores into intestinal epithelial cells contributes to recurrence of Clostridioides difficile infection

by Pablo Castro-Córdova, Paola Mora-Uribe, Rodrigo Reyes-Ramírez, Glenda Cofré-Araneda, Josué Orozco-Aguilar, Christian Brito-Silva, María José Mendoza-León, Sarah A. Kuehne, Nigel P. Minton, Marjorie Pizarro-Guajardo, Daniel Paredes-Sabja
Published 2021-02-01