RVX-208, an inducer of ApoA-I in humans, is a BET bromodomain antagonist.

by Kevin G McLure, Emily M Gesner, Laura Tsujikawa, Olesya A Kharenko, Sarah Attwell, Eric Campeau, Sylwia Wasiak, Adam Stein, Andre White, Eric Fontano, Robert K Suto, Norman C W Wong, Gregory S Wagner, Henrik C Hansen, Peter R Young
Published 2013-01-01

Checkpoint inhibition through small molecule-induced internalization of programmed death-ligand 1

by Jang-June Park, Emily P. Thi, Victor H. Carpio, Yingzhi Bi, Andrew G. Cole, Bruce D. Dorsey, Kristi Fan, Troy Harasym, Christina L. Iott, Salam Kadhim, Jin Hyang Kim, Amy C. H. Lee, Duyan Nguyen, Bhavna S. Paratala, Ruiqing Qiu, Andre White, Damodharan Lakshminarasimhan, Christopher Leo, Robert K. Suto, Rene Rijnbrand, Sunny Tang, Michael J. Sofia, Chris B. Moore
Published 2021-02-01