Bacterial lipids: powerful modifiers of the innate immune response [version 1; referees: 2 approved]

by Courtney E. Chandler, Robert K. Ernst
Published 2017-08-01

Antimicrobial peptide activity is anticorrelated with lipid a leaflet affinity.

by Nathaniel Nelson, Belita Opene, Robert K Ernst, Daniel K Schwartz
Published 2020-01-01

Influence of Lipid A Acylation Pattern on Membrane Permeability and Innate Immune Stimulation

by Robert K. Ernst, Xiaoyuan Wang, Jiuzhou Chen, Zhou Wang, Yanyan Li
Published 2013-08-01

Analysis of Pseudomonas aeruginosa biofilm membrane vesicles supports multiple mechanisms of biogenesis.

by Adam C Cooke, Alexander V Nello, Robert K Ernst, Jeffrey W Schertzer
Published 2019-01-01

Expression level of human TLR4 rather than sequence is the key determinant of LPS responsiveness.

by Adeline M Hajjar, Robert K Ernst, Jaehun Yi, Cathy S Yam, Samuel I Miller
Published 2017-01-01

Maintenance of Deep Lung Architecture and Automated Airway Segmentation for 3D Mass Spectrometry Imaging

by Alison J. Scott, Courtney E. Chandler, Shane R. Ellis, Ron M. A. Heeren, Robert K. Ernst
Published 2019-12-01

Identification of the ESKAPE pathogens by mass spectrometric analysis of microbial membrane glycolipids

by Lisa M. Leung, William E. Fondrie, Yohei Doi, J. Kristie Johnson, Dudley K. Strickland, Robert K. Ernst, David R. Goodlett
Published 2017-07-01

Comprehensive analysis of clinical Burkholderia pseudomallei isolates demonstrates conservation of unique lipid A structure and TLR4-dependent innate immune activation.

by Sineenart Sengyee, Sung Hwan Yoon, Suporn Paksanont, Thatcha Yimthin, Vanaporn Wuthiekanun, Direk Limmathurotsakul, T Eoin West, Robert K Ernst, Narisara Chantratita
Published 2018-02-01

Characterization of BPSS1521 (bprD), a regulator of Burkholderia pseudomallei virulence gene expression in the mouse model.

by Sunisa Chirakul, Thanatchaporn Bartpho, Thidathip Wongsurawat, Suwimol Taweechaisupapong, Nitsara Karoonutaisiri, Adel M Talaat, Surasakdi Wongratanacheewin, Robert K Ernst, Rasana W Sermswan
Published 2014-01-01

Mutations of Francisella novicida that alter the mechanism of its phagocytosis by murine macrophages.

by Xin-He Lai, Renee L Shirley, Lidia Crosa, Duangjit Kanistanon, Rebecca Tempel, Robert K Ernst, Larry A Gallagher, Colin Manoil, Fred Heffron
Published 2010-07-01

A pilot study of an anti-endotoxin Ig-enriched bovine colostrum to prevent experimental sepsis

by Alan S Cross, Steven M Opal, John E Palardy, Surekha Shridhar, Scott M Baliban, Alison J Scott, Abdullah B Chahin, Robert K Ernst
Published 2021-05-01

Increased long chain acyl-Coa synthetase activity and fatty acid import is linked to membrane synthesis for development of picornavirus replication organelles.

by Jules A Nchoutmboube, Ekaterina G Viktorova, Alison J Scott, Lauren A Ford, Zhengtong Pei, Paul A Watkins, Robert K Ernst, George A Belov
Published 2013-01-01

Humanized TLR4/MD-2 mice reveal LPS recognition differentially impacts susceptibility to Yersinia pestis and Salmonella enterica.

by Adeline M Hajjar, Robert K Ernst, Edgardo S Fortuno, Alicia S Brasfield, Cathy S Yam, Lindsay A Newlon, Tobias R Kollmann, Samuel I Miller, Christopher B Wilson
Published 2012-01-01

Lipid A Structural Divergence in <i>Rickettsia</i> Pathogens

by Mark L. Guillotte, Courtney E. Chandler, Victoria I. Verhoeve, Joseph J. Gillespie, Timothy P. Driscoll, M. Sayeedur Rahman, Robert K. Ernst, Abdu F. Azad
Published 2021-06-01

Rapid microbial identification and colistin resistance detection via MALDI-TOF MS using a novel on-target extraction of membrane lipids

by Matthew Sorensen, Courtney E. Chandler, Francesca M. Gardner, Salma Ramadan, Prasanna D. Khot, Lisa M. Leung, Christine E. Farrance, David R. Goodlett, Robert K. Ernst, Erik Nilsson
Published 2020-12-01

Rationally Designed TLR4 Ligands for Vaccine Adjuvant Discovery

by Kelsey A. Gregg, Erin Harberts, Francesca M. Gardner, Mark R. Pelletier, Corinne Cayatte, Li Yu, Michael P. McCarthy, Jason D. Marshall, Robert K. Ernst, Nancy E. Freitag
Published 2017-05-01

Evaluation of the ability of LL-37 to neutralise LPS in vitro and ex vivo.

by Aaron Scott, Sinéad Weldon, Paul J Buchanan, Bettina Schock, Robert K Ernst, Danny F McAuley, Michael M Tunney, Chris R Irwin, J Stuart Elborn, Clifford C Taggart
Published 2011-01-01

A Francisella mutant in lipid A carbohydrate modification elicits protective immunity.

by Duangjit Kanistanon, Adeline M Hajjar, Mark R Pelletier, Larry A Gallagher, Thomas Kalhorn, Scott A Shaffer, David R Goodlett, Laurence Rohmer, Mitchell J Brittnacher, Shawn J Skerrett, Robert K Ernst
Published 2008-02-01

Effect of Two Unique Nanoparticle Formulations on the Efficacy of a Broadly Protective Vaccine Against Pseudomonas Aeruginosa

by Debaki R. Howlader, Sayan Das, Ti Lu, Gang Hu, David J. Varisco, Zackary K. Dietz, Sierra P. Walton, Siva Sai Kumar Ratnakaram, Francesca M. Gardner, Robert K. Ernst, William D. Picking, Wendy L. Picking
Published 2021-08-01

Survey of innate immune responses to Burkholderia pseudomallei in human blood identifies a central role for lipopolysaccharide.

by Narisara Chantratita, Sarunporn Tandhavanant, Nicolle D Myers, Sudeshna Seal, Arkhom Arayawichanont, Aroonsri Kliangsa-Ad, Lauren E Hittle, Robert K Ernst, Mary J Emond, Mark M Wurfel, Nicholas P J Day, Sharon J Peacock, T Eoin West
Published 2013-01-01