Immunomodulatory factors galectin-9 and interferon-gamma synergize to induce expression of rate-limiting enzymes of the Kynurenine Pathway in the mouse hippocampus

by Alexandra K Brooks, Alexandra K Brooks, Alexandra K Brooks, Marcus A Lawson, Marcus A Lawson, Marcus A Lawson, Jennifer L Rytych, Jennifer L Rytych, Kevin C Yu, Kevin C Yu, Tiffany M Janda, Tiffany M Janda, Andrew J Steelman, Andrew J Steelman, Andrew J Steelman, Andrew J Steelman, Robert H McCusker, Robert H McCusker, Robert H McCusker, Robert H McCusker
Published 2016-10-01

Glial and tissue-specific regulation of Kynurenine Pathway dioxygenases by acute stress of mice

by Carlos R. Dostal, Megan Carson Sulzer, Keith W. Kelley, Gregory G. Freund, Robert H. McCusker
Published 2017-12-01

Deletion of indoleamine 2,3 dioxygenase (Ido)1 but not Ido2 exacerbates disease symptoms of MOG35-55-induced experimental autoimmune encephalomyelitis

by Lisa A. Wetzel, Myrna Hurtado, Zoe A. MacDowell Kaswan, Robert H. McCusker, Andrew J. Steelman
Published 2020-08-01

Differential Transcriptome Networks between IDO1-Knockout and Wild-Type Mice in Brain Microglia and Macrophages.

by Dianelys Gonzalez-Pena, Scott E Nixon, Bruce R Southey, Marcus A Lawson, Robert H McCusker, Alvaro G Hernandez, Robert Dantzer, Keith W Kelley, Sandra L Rodriguez-Zas
Published 2016-01-01

Microglia Transcriptome Changes in a Model of Depressive Behavior after Immune Challenge.

by Dianelys Gonzalez-Pena, Scott E Nixon, Jason C O'Connor, Bruce R Southey, Marcus A Lawson, Robert H McCusker, Tania Borras, Debbie Machuca, Alvaro G Hernandez, Robert Dantzer, Keith W Kelley, Sandra L Rodriguez-Zas
Published 2016-01-01

Immunosuppressive IDO in Cancer: Mechanisms of Action, Animal Models, and Targeting Strategies

by Lijie Zhai, April Bell, Erik Ladomersky, Kristen L. Lauing, Lakshmi Bollu, Jeffrey A. Sosman, Jeffrey A. Sosman, Bin Zhang, Bin Zhang, Bin Zhang, Jennifer D. Wu, Jennifer D. Wu, Jennifer D. Wu, Stephen D. Miller, Stephen D. Miller, Joshua J. Meeks, Joshua J. Meeks, Joshua J. Meeks, Rimas V. Lukas, Rimas V. Lukas, Eugene Wyatt, Eugene Wyatt, Lynn Doglio, Lynn Doglio, Gary E. Schiltz, Gary E. Schiltz, Gary E. Schiltz, Robert H. McCusker, Derek A. Wainwright, Derek A. Wainwright, Derek A. Wainwright, Derek A. Wainwright
Published 2020-06-01