Outcome Measures Used in Ocular Gene Therapy Trials: A Scoping Review of Current Practice

by Jasleen K. Jolly, Jasleen K. Jolly, Jasleen K. Jolly, Holly Bridge, Robert E. MacLaren, Robert E. MacLaren
Published 2019-09-01

Optogenetic Gene Therapy for the Degenerate Retina: Recent Advances

by Michelle E. McClements, Federica Staurenghi, Robert E. MacLaren, Robert E. MacLaren, Jasmina Cehajic-Kapetanovic, Jasmina Cehajic-Kapetanovic
Published 2020-11-01

CRISPR-Cas9 DNA Base-Editing and Prime-Editing

by Ariel Kantor, Michelle E. McClements, Robert E. MacLaren
Published 2020-08-01

Molecular Therapies for Choroideremia

by Jasmina Cehajic Kapetanovic, Alun R. Barnard, Robert E. MacLaren
Published 2019-09-01

Insights on the Regeneration Potential of Müller Glia in the Mammalian Retina

by Ahmed Salman, Michelle E. McClements, Robert E. MacLaren
Published 2021-07-01

Therapy Approaches for Stargardt Disease

by Elena Piotter, Michelle E McClements, Robert E MacLaren
Published 2021-08-01

Outcome of Full-Thickness Macular Hole Surgery in Choroideremia

by Mays Talib, Leonoor S. Koetsier, Robert E. MacLaren, Camiel J.F. Boon
Published 2017-07-01

CRISPR Interference–Potential Application in Retinal Disease

by Caroline F. Peddle, Lewis E. Fry, Michelle E. McClements, Robert E. MacLaren
Published 2020-03-01

Exploring the Variable Phenotypes of <i>RPGR</i> Carrier Females in Assessing Their Potential for Retinal Gene Therapy

by Anika Nanda, Anna P. Salvetti, Penny Clouston, Susan M. Downes, Robert E. MacLaren
Published 2018-12-01

Accurate Quantification of AAV Vector Genomes by Quantitative PCR

by Cristina Martinez-Fernandez de la Camara, Michelle E. McClements, Robert E. MacLaren
Published 2021-04-01

The Biological Activity of AAV Vectors for Choroideremia Gene Therapy Can Be Measured by In Vitro Prenylation of RAB6A

by Maria I. Patrício, Alun R. Barnard, Christopher I. Cox, Clare Blue, Robert E. MacLaren
Published 2018-06-01

Inclusion of the Woodchuck Hepatitis Virus Posttranscriptional Regulatory Element Enhances AAV2-Driven Transduction of Mouse and Human Retina

by Maria I. Patrício, Alun R. Barnard, Harry O. Orlans, Michelle E. McClements, Robert E. MacLaren
Published 2017-03-01

Molecular Strategies for RPGR Gene Therapy

by Jasmina Cehajic Kapetanovic, Michelle E McClements, Cristina Martinez-Fernandez de la Camara, Robert E MacLaren
Published 2019-09-01

RNA Editing as a Therapeutic Approach for Retinal Gene Therapy Requiring Long Coding Sequences

by Lewis E. Fry, Caroline F. Peddle, Alun R. Barnard, Michelle E. McClements, Robert E. MacLaren
Published 2020-01-01

Real-world refractive outcomes of toric intraocular lens implantation in a United Kingdom National Health Service setting

by Kanmin Xue, Jasleen K. Jolly, Sonia P. Mall, Shreya Haldar, Paul H. Rosen, Robert E. MacLaren
Published 2018-02-01

AAV Induced Expression of Human Rod and Cone Opsin in Bipolar Cells of a Mouse Model of Retinal Degeneration

by Michelle E. McClements, Federica Staurenghi, Meike Visel, John G. Flannery, Robert E. MacLaren, Jasmina Cehajic-Kapetanovic
Published 2021-01-01

Longitudinal Study to Assess the Quantitative Use of Fundus Autofluorescence for Monitoring Disease Progression in Choroideremia

by Adam M Dubis, Wei S Lim, Jasleen K Jolly, Maria Toms, Robert E MacLaren, Andrew R Webster, Mariya Moosajee
Published 2021-01-01

Analysis of Early Cone Dysfunction in an In Vivo Model of Rod-Cone Dystrophy

by Mark M. Hassall, Michelle E. McClements, Alun R. Barnard, Maria í. Patricio, Sher A. Aslam, Robert E. Maclaren
Published 2020-08-01

Immunomodulatory Effects of Hydroxychloroquine and Chloroquine in Viral Infections and Their Potential Application in Retinal Gene Therapy

by Laurel C. Chandler, Imran H. Yusuf, Michelle E. McClements, Alun R. Barnard, Robert E. MacLaren, Kanmin Xue
Published 2020-07-01

Non-image-forming light driven functions are preserved in a mouse model of autosomal dominant optic atrophy.

by Georgia Perganta, Alun R Barnard, Christiana Katti, Athanasios Vachtsevanos, Ron H Douglas, Robert E MacLaren, Marcela Votruba, Sumathi Sekaran
Published 2013-01-01