Low Evolutionary Selection Pressure in Senescence Does Not Explain the Persistence of Aβ in the Vertebrate Genome

by Robert D. Moir, Rudolph E. Tanzi
Published 2019-03-01

Non-conjugated small molecule FRET for differentiating monomers from higher molecular weight amyloid beta species.

by Chongzhao Ran, Wei Zhao, Robert D Moir, Anna Moore
Published 2011-04-01

Synaptic abnormalities in a Drosophila model of Alzheimer’s disease

by Siddhita D. Mhatre, Vivek Satyasi, Mark Killen, Brie E. Paddock, Robert D. Moir, Aleister J. Saunders, Daniel R. Marenda
Published 2014-03-01

Anesthetic propofol attenuates the isoflurane-induced caspase-3 activation and Aβ oligomerization.

by Yiying Zhang, Yu Zhen, Yuanlin Dong, Zhipeng Xu, Yun Yue, Todd E Golde, Rudolph E Tanzi, Robert D Moir, Zhongcong Xie
Published 2011-01-01

The Alzheimer's disease-associated amyloid beta-protein is an antimicrobial peptide.

by Stephanie J Soscia, James E Kirby, Kevin J Washicosky, Stephanie M Tucker, Martin Ingelsson, Bradley Hyman, Mark A Burton, Lee E Goldstein, Scott Duong, Rudolph E Tanzi, Robert D Moir
Published 2010-03-01

Alzheimer's disease amyloid-beta links lens and brain pathology in Down syndrome.

by Juliet A Moncaster, Roberto Pineda, Robert D Moir, Suqian Lu, Mark A Burton, Joy G Ghosh, Maria Ericsson, Stephanie J Soscia, Anca Mocofanescu, Rebecca D Folkerth, Richard M Robb, Jer R Kuszak, John I Clark, Rudolph E Tanzi, David G Hunter, Lee E Goldstein
Published 2010-05-01

Characterization of a Drosophila Alzheimer's disease model: pharmacological rescue of cognitive defects.

by Ranjita Chakraborty, Vidya Vepuri, Siddhita D Mhatre, Brie E Paddock, Sean Miller, Sarah J Michelson, Radha Delvadia, Arkit Desai, Marianna Vinokur, David J Melicharek, Suruchi Utreja, Preeti Khandelwal, Sara Ansaloni, Lee E Goldstein, Robert D Moir, Jeremy C Lee, Loni P Tabb, Aleister J Saunders, Daniel R Marenda
Published 2011-01-01