Granulomatosis with polyangiitis in a patient treated with dabrafenib and trametinib for BRAF V600E positive lung adenocarcinoma

by Anastasios Dimou, Gregory Barron, Daniel T. Merrick, Jason Kolfenbach, Robert C. Doebele
Published 2020-03-01

A Changing of the Guard: Immune Checkpoint Inhibitors With and Without Chemotherapy as First Line Treatment for Metastatic Non-small Cell Lung Cancer

by Jose M. Pacheco, D. Ross Camidge, Robert C. Doebele, Erin Schenk
Published 2019-03-01

A novel interplay between Rap1 and PKA regulates induction of angiogenesis in prostate cancer.

by Jyotsana Menon, Robert C Doebele, Suzana Gomes, Elena Bevilacqua, Katie M Reindl, Marsha Rich Rosner
Published 2012-01-01

Activity of tarloxotinib‐E in cells with EGFR exon‐20 insertion mutations and mechanisms of acquired resistance

by Masaya Nishino, Kenichi Suda, Takamasa Koga, Shuta Ohara, Toshio Fujino, Junichi Soh, Vijaya Tirunagaru, Avanish Vellanki, Robert C. Doebele, Tetsuya Mitsudomi
Published 2021-05-01

Cecal Volvulus as a Rare Complication of Osimertinib Dosed at 160 mg in Patients With EGFR-Mutant Non-small Cell Lung Cancer

by Tejas Patil, Jose M. Pacheco, Anastasios Dimou, William T. Purcell, Candice Rossi, Paul A. Bunn, Robert C. Doebele, D. Ross Camidge, Lisa Ferrigno
Published 2020-04-01

Rapidly acquired resistance to EGFR tyrosine kinase inhibitors in NSCLC cell lines through de-repression of FGFR2 and FGFR3 expression.

by Kathryn E Ware, Marianne E Marshall, Lydia R Heasley, Lindsay Marek, Trista K Hinz, Paula Hercule, Barbara A Helfrich, Robert C Doebele, Lynn E Heasley
Published 2010-11-01

High dose acetaminophen inhibits STAT3 and has free radical independent anti-cancer stem cell activity

by Pavani Pingali, Y. Jeffrey Wu, Rio Boothello, Chetna Sharon, Howard Li, Srinivas Sistla, Nehru Viji Sankaranarayanan, Umesh R. Desai, Anh T. Le, Robert C. Doebele, Leslie L. Muldoon, Bhaumik B. Patel, Alexander Neuwelt
Published 2021-03-01

Cancer cell-intrinsic expression of MHC II in lung cancer cell lines is actively restricted by MEK/ERK signaling and epigenetic mechanisms

by Alexander J Neuwelt, Abigail K Kimball, Amber M Johnson, Benjamin W Arnold, Bonnie L Bullock, Rachael E Kaspar, Jeff W Kwak, Meng-Han Wu, Lynn E Heasley, Robert C Doebele, Howard Y Li
Published 2020-06-01

A tyrosine kinase inhibitor-induced interferon response positively associates with clinical response in EGFR-mutant lung cancer

by Natalia J. Gurule, Caroline E. McCoach, Trista K. Hinz, Daniel T. Merrick, Adriaan Van Bokhoven, Jihye Kim, Tejas Patil, Jacob Calhoun, Raphael A. Nemenoff, Aik Choon Tan, Robert C. Doebele, Lynn E. Heasley
Published 2021-05-01

Resistance to ROS1 inhibition mediated by EGFR pathway activation in non-small cell lung cancer.

by Kurtis D Davies, Sakshi Mahale, David P Astling, Dara L Aisner, Anh T Le, Trista K Hinz, Aria Vaishnavi, Paul A Bunn, Lynn E Heasley, Aik-Choon Tan, D Ross Camidge, Marileila Varella-Garcia, Robert C Doebele
Published 2013-01-01