Regulation of Polyamine Metabolism by Curcumin for Cancer Prevention and Therapy

by Tracy Murray-Stewart, Robert A. Casero
Published 2017-12-01

Polyamine Homeostasis in Snyder-Robinson Syndrome

by Tracy Murray-Stewart, Matthew Dunworth, Jackson R. Foley, Charles E. Schwartz, Robert A. Casero
Published 2018-12-01

Curcumin mediates polyamine metabolism and sensitizes gastrointestinal cancer cells to antitumor polyamine-targeted therapies.

by Tracy Murray-Stewart, Matthew Dunworth, Yuan Lui, Francis M Giardiello, Patrick M Woster, Robert A Casero
Published 2018-01-01

Elucidating the Structure of N1‑Acetylisoputreanine: A Novel Polyamine Catabolite in Human Urine

by Bryna L. Fitzgerald, Sebabrata Mahapatra, Delphine K. Farmer, Michael R. McNeil, Robert A. Casero, John T. Belisle
Published 2017-07-01

Correction: Biochemical evaluation of the anticancer potential of the polyamine-based nanocarrier Nano11047.

by Tracy Murray-Stewart, Elena Ferrari, Ying Xie, Fei Yu, Laurence J Marton, David Oupicky, Robert A Casero
Published 2017-01-01

Biochemical evaluation of the anticancer potential of the polyamine-based nanocarrier Nano11047.

by Tracy Murray-Stewart, Elena Ferrari, Ying Xie, Fei Yu, Laurence J Marton, David Oupicky, Robert A Casero
Published 2017-01-01

Proximal tubule epithelial cell specific ablation of the spermidine/spermine N1-acetyltransferase gene reduces the severity of renal ischemia/reperfusion injury.

by Kamyar Zahedi, Sharon Barone, Yang Wang, Tracy Murray-Stewart, Prabir Roy-Chaudhury, Roger D Smith, Robert A Casero, Manoocher Soleimani
Published 2014-01-01

Difluoromethylornithine is a novel inhibitor of Helicobacter pylori growth, CagA translocation, and interleukin-8 induction.

by Daniel P Barry, Mohammad Asim, David A Leiman, Thibaut de Sablet, Kshipra Singh, Robert A Casero, Rupesh Chaturvedi, Keith T Wilson
Published 2011-02-01

Activation of endoplasmic reticulum stress response by enhanced polyamine catabolism is important in the mediation of cisplatin-induced acute kidney injury.

by Kamyar Zahedi, Sharon Barone, Christina Destefano-Shields, Marybeth Brooks, Tracy Murray-Stewart, Matthew Dunworth, Weimin Li, Joanne R Doherty, Mark A Hall, Roger D Smith, John L Cleveland, Robert A Casero, Manoocher Soleimani
Published 2017-01-01

MOF Acetylates the Histone Demethylase LSD1 to Suppress Epithelial-to-Mesenchymal Transition

by Huacheng Luo, Anitha K. Shenoy, Xuehui Li, Yue Jin, Lihua Jin, Qingsong Cai, Ming Tang, Yang Liu, Hao Chen, David Reisman, Lizi Wu, Edward Seto, Yi Qiu, Yali Dou, Robert A. Casero Jr., Jianrong Lu
Published 2016-06-01

Ablation of polyamine catabolic enzymes provokes Purkinje cell damage, neuroinflammation, and severe ataxia

by Kamyar Zahedi, Marybeth Brooks, Sharon Barone, Negah Rahmati, Tracy Murray Stewart, Matthew Dunworth, Christina Destefano-Shields, Nupur Dasgupta, Steve Davidson, Diana M. Lindquist, Christine E. Fuller, Roger D. Smith, John L. Cleveland, Robert A. Casero, Manoocher Soleimani
Published 2020-10-01

L-arginine supplementation improves responses to injury and inflammation in dextran sulfate sodium colitis.

by Lori A Coburn, Xue Gong, Kshipra Singh, Mohammad Asim, Brooks P Scull, Margaret M Allaman, Christopher S Williams, Michael J Rosen, M Kay Washington, Daniel P Barry, M Blanca Piazuelo, Robert A Casero, Rupesh Chaturvedi, Zhongming Zhao, Keith T Wilson
Published 2012-01-01

Pharmacological polyamine catabolism upregulation with methionine salvage pathway inhibition as an effective prostate cancer therapy

by Hayley C. Affronti, Aryn M. Rowsam, Anthony J. Pellerite, Spencer R. Rosario, Mark D. Long, Justine J. Jacobi, Anna Bianchi-Smiraglia, Christoph S. Boerlin, Bryan M. Gillard, Ellen Karasik, Barbara A. Foster, Michael Moser, John H. Wilton, Kristopher Attwood, Mikhail A. Nikiforov, Gissou Azabdaftari, Roberto Pili, James G. Phillips, Robert A. Casero, Dominic J. Smiraglia
Published 2020-01-01

Distinct Immunomodulatory Effects of Spermine Oxidase in Colitis Induced by Epithelial Injury or Infection

by Alain P. Gobert, Alain P. Gobert, Nicole T. Al-Greene, Kshipra Singh, Kshipra Singh, Lori A. Coburn, Lori A. Coburn, Lori A. Coburn, Johanna C. Sierra, Johanna C. Sierra, Thomas G. Verriere, Paula B. Luis, Claus Schneider, Claus Schneider, Mohammad Asim, Margaret M. Allaman, Daniel P. Barry, John L. Cleveland, John L. Cleveland, Christina E. Destefano Shields, Robert A. Casero, M. Kay Washington, M. Blanca Piazuelo, M. Blanca Piazuelo, Keith T. Wilson, Keith T. Wilson, Keith T. Wilson, Keith T. Wilson
Published 2018-06-01