Anti-inflammatory treatment with acetylsalicylate or rofecoxib is not neuroprotective in Huntington's disease transgenic mice

by Fran Norflus, Agnes Nanje, Claire-Anne Gutekunst, Geming Shi, Joshua Cohen, Michelle Bejarano, Jonathan Fox, Robert J. Ferrante, Steven M. Hersch
Published 2004-11-01

Mice lacking alpha-synuclein are resistant to mitochondrial toxins

by Peter Klivenyi, Donald Siwek, Gabrielle Gardian, Lichuan Yang, Anatoly Starkov, Carine Cleren, Robert J. Ferrante, Neil W. Kowall, Asa Abeliovich, M. Flint Beal
Published 2006-03-01

Huntington's Disease of the Endocrine Pancreas: Insulin Deficiency and Diabetes Mellitus due to Impaired Insulin Gene Expression

by Ole A. Andreassen, Alpaslan Dedeoglu, Violeta Stanojevic, Duncan B. Hughes, Susan E. Browne, Colin A. Leech, Robert J. Ferrante, Joel F. Habener, M.Flint Beal, Melissa K. Thomas
Published 2002-12-01

The Sirtuin 2 Inhibitor AK-7 Is Neuroprotective in Huntington’s Disease Mouse Models

by Vanita Chopra, Luisa Quinti, Jinho Kim, Lorraine Vollor, K. Lakshmi Narayanan, Christina Edgerly, Patricia M. Cipicchio, Molly A. Lauver, Soo Hyuk Choi, Richard B. Silverman, Robert J. Ferrante, Steven Hersch, Aleksey G. Kazantsev
Published 2012-12-01

Melatonin inhibits the caspase-1/cytochrome c/caspase-3 cell death pathway, inhibits MT1 receptor loss and delays disease progression in a mouse model of amyotrophic lateral sclero...

by Yi Zhang, Anna Cook, Jinho Kim, Sergei V. Baranov, Jiying Jiang, Karen Smith, Kerry Cormier, Erik Bennett, Robert P. Browser, Arthur L. Day, Diane L. Carlisle, Robert J. Ferrante, Xin Wang, Robert M. Friedlander
Published 2013-07-01

Creatine Increases Survival and Delays Motor Symptoms in a Transgenic Animal Model of Huntington's Disease

by Ole A. Andreassen, Alpaslan Dedeoglu, Robert J. Ferrante, Bruce G. Jenkins, Kimberly L. Ferrante, Melissa Thomas, Avi Friedlich, Susan E. Browne, Gabriele Schilling, David R. Borchelt, Steven M. Hersch, Christopher A. Ross, M.Flint Beal
Published 2001-06-01

The Wnt receptor Ryk reduces neuronal and cell survival capacity by repressing FOXO activity during the early phases of mutant huntingtin pathogenicity.

by Cendrine Tourette, Francesca Farina, Rafael P Vazquez-Manrique, Anne-Marie Orfila, Jessica Voisin, Sonia Hernandez, Nicolas Offner, J Alex Parker, Sophie Menet, Jinho Kim, Jungmok Lyu, Si Ho Choi, Kerry Cormier, Christina K Edgerly, Olivia L Bordiuk, Karen Smith, Anne Louise, Michael Halford, Steven Stacker, Jean-Philippe Vert, Robert J Ferrante, Wange Lu, Christian Neri
Published 2014-06-01