The Immunological Factors Predisposing to Severe Covid-19 Are Already Present in Healthy Elderly and Men

by Gizem Kilic, Ozlem Bulut, Martin Jaeger, Rob ter Horst, Rob ter Horst, Valerie A. C. M. Koeken, Valerie A. C. M. Koeken, Simone J. C. F. M. Moorlag, Vera P. Mourits, Charlotte de Bree, Jorge Domínguez-Andrés, Leo A. B. Joosten, Mihai G. Netea, Mihai G. Netea
Published 2021-08-01

Involvement of Lactate and Pyruvate in the Anti-Inflammatory Effects Exerted by Voluntary Activation of the Sympathetic Nervous System

by Jelle Zwaag, Rob ter Horst, Ivana Blaženović, Daniel Stoessel, Jacqueline Ratter, Josephine M. Worseck, Nicolas Schauer, Rinke Stienstra, Mihai G. Netea, Dieter Jahn, Peter Pickkers, Matthijs Kox
Published 2020-04-01

Integrative Genomics-Based Discovery of Novel Regulators of the Innate Antiviral Response.

by Robin van der Lee, Qian Feng, Martijn A Langereis, Rob Ter Horst, Radek Szklarczyk, Mihai G Netea, Arno C Andeweg, Frank J M van Kuppeveld, Martijn A Huynen
Published 2015-10-01

An integrative model of cardiometabolic traits identifies two types of metabolic syndrome

by Amit Frishberg, Inge van den Munckhof, Rob ter Horst, Kiki Schraa, Leo AB Joosten, Joost HW Rutten, Adrian C Iancu, Ioana M Dregoesc, Bogdan A Tigu, Mihai G Netea, Niels P Riksen, Irit Gat-Viks
Published 2021-01-01

A possible role for mitochondrial-derived peptides humanin and MOTS-c in patients with Q fever fatigue syndrome and chronic fatigue syndrome

by Ruud P. H. Raijmakers, Anne F. M. Jansen, Stephan P. Keijmel, Rob ter Horst, Megan E. Roerink, Boris Novakovic, Leo A. B. Joosten, Jos W. M. van der Meer, Mihai G. Netea, Chantal P. Bleeker-Rovers
Published 2019-05-01

Comparative host transcriptome in response to pathogenic fungi identifies common and species-specific transcriptional antifungal host response pathways

by Mariolina Bruno, Intan M.W. Dewi, Vicky Matzaraki, Rob ter Horst, Marina Pekmezovic, Berenice Rösler, Laszlo Groh, Rutger J. Röring, Vinod Kumar, Yang Li, Agostinho Carvalho, Mihai G. Netea, Jean-Paul Latgé, Mark S. Gresnigt, Frank L. van de Veerdonk
Published 2021-01-01

Rewiring monocyte glucose metabolism via C-type lectin signaling protects against disseminated candidiasis.

by Jorge Domínguez-Andrés, Rob J W Arts, Rob Ter Horst, Mark S Gresnigt, Sanne P Smeekens, Jacqueline M Ratter, Ekta Lachmandas, Lily Boutens, Frank L van de Veerdonk, Leo A B Joosten, Richard A Notebaart, Carlos Ardavín, Mihai G Netea
Published 2017-09-01

Chronic HIV infection induces transcriptional and functional reprogramming of innate immune cells

by Wouter A. van der Heijden, Lisa Van de Wijer, Farid Keramati, Wim Trypsteen, Sofie Rutsaert, Rob ter Horst, Martin Jaeger, Hans J.P.M. Koenen, Hendrik G. Stunnenberg, Irma Joosten, Paul E. Verweij, Jan van Lunzen, Charles A. Dinarello, Leo A.B. Joosten, Linos Vandekerckhove, Mihai G. Netea, André J.A.M. van der Ven, Quirijn de Mast
Published 2021-04-01

Genetic and Microbial Associations to Plasma and Fecal Bile Acids in Obesity Relate to Plasma Lipids and Liver Fat Content

by Lianmin Chen, Inge C.L. van den Munckhof, Kiki Schraa, Rob ter Horst, Martijn Koehorst, Martijn van Faassen, Claude van der Ley, Marwah Doestzada, Daria V. Zhernakova, Alexander Kurilshikov, Vincent W. Bloks, Albert K. Groen, Niels P. Riksen, Joost H.W. Rutten, Leo A.B. Joosten, Cisca Wijmenga, Alexandra Zhernakova, Mihai G. Netea, Jingyuan Fu, Folkert Kuipers
Published 2020-10-01

The Architecture of Circulating Immune Cells Is Dysregulated in People Living With HIV on Long Term Antiretroviral Treatment and Relates With Markers of the HIV-1 Reservoir, Cytome...

by Lisa Van de Wijer, Wouter A. van der Heijden, Rob ter Horst, Martin Jaeger, Wim Trypsteen, Sofie Rutsaert, Bram van Cranenbroek, Esther van Rijssen, Irma Joosten, Leo Joosten, Linos Vandekerckhove, Till Schoofs, Jan van Lunzen, Mihai G. Netea, Mihai G. Netea, Hans J.P.M. Koenen, André J.A.M. van der Ven, Quirijn de Mast
Published 2021-04-01

Polymorphisms within Autophagy-Related Genes Influence the Risk of Developing Colorectal Cancer: A Meta-Analysis of Four Large Cohorts

by Juan Sainz, Francisco José García-Verdejo, Manuel Martínez-Bueno, Abhishek Kumar, José Manuel Sánchez-Maldonado, Anna Díez-Villanueva, Ludmila Vodičková, Veronika Vymetálková, Vicente Martin Sánchez, Miguel Inacio Da Silva Filho, Belém Sampaio-Marques, Stefanie Brezina, Katja Butterbach, Rob ter Horst, Michael Hoffmeister, Paula Ludovico, Manuel Jurado, Yang Li, Pedro Sánchez-Rovira, Mihai G. Netea, Andrea Gsur, Pavel Vodička, Víctor Moreno, Kari Hemminki, Hermann Brenner, Jenny Chang-Claude, Asta Försti
Published 2021-03-01

Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunity

by Samuel M. Gonçalves, Cláudio Duarte-Oliveira, Cláudia F. Campos, Vishukumar Aimanianda, Rob ter Horst, Luis Leite, Toine Mercier, Paulo Pereira, Miguel Fernández-García, Daniela Antunes, Cláudia S. Rodrigues, Catarina Barbosa-Matos, Joana Gaifem, Inês Mesquita, António Marques, Nuno S. Osório, Egídio Torrado, Fernando Rodrigues, Sandra Costa, Leo AB. Joosten, Katrien Lagrou, Johan Maertens, João F. Lacerda, António Campos, Gordon D. Brown, Axel A. Brakhage, Coral Barbas, Ricardo Silvestre, Frank L. van de Veerdonk, Georgios Chamilos, Mihai G. Netea, Jean-Paul Latgé, Cristina Cunha, Agostinho Carvalho
Published 2020-05-01

Polymorphisms within the <i>TNFSF4</i> and <i>MAPKAPK2</i> Loci Influence the Risk of Developing Invasive Aspergillosis: A Two-Stage Case Control Study in the Context of the aspBIO...

by Jose Manuel Sánchez-Maldonado, Ana Moñiz-Díez, Rob ter Horst, Daniele Campa, Antonio José Cabrera-Serrano, Manuel Martínez-Bueno, María del Pilar Garrido-Collado, Francisca Hernández-Mohedo, Laura Fernández-Puerta, Miguel Ángel López-Nevot, Cristina Cunha, Pedro Antonio González-Sierra, Jan Springer, Michaela Lackner, Laura Alcazar-Fuoli, Luana Fianchi, José María Aguado, Livio Pagano, Elisa López-Fernández, Esther Clavero, Leonardo Potenza, Mario Luppi, Lucia Moratalla, Carlos Solano, Antonio Sampedro, Manuel Cuenca-Estrella, Cornelia Lass-Flörl, Federico Canzian, Juergen Loeffler, Yang Li, Hermann Einsele, Mihai G. Netea, Lourdes Vázquez, Agostinho Carvalho, Manuel Jurado, Juan Sainz, on behalf of the PCRAGA Study Group
Published 2021-12-01