CARbodies: Human Antibodies Against Cell Surface Tumor Antigens Selected From Repertoires Displayed on T Cell Chimeric Antigen Receptors

by Vanesa Alonso-Camino, David Sánchez-Martín, Marta Compte, Natalia Nuñez-Prado, Rosa M Diaz, Richard Vile, Luis Alvarez-Vallina
Published 2013-01-01

Oncolytic Reovirus-Mediated Recruitment of Early Innate Immune Responses Reverses Immunotherapy Resistance in Prostate Tumors

by Nicola E. Annels, Guy R. Simpson, Mick Denyer, Mehreen Arif, Matt Coffey, Alan Melcher, Kevin Harrington, Richard Vile, Hardev Pandha
Published 2021-03-01

Antiviral antibody responses to systemic administration of an oncolytic RNA virus: the impact of standard concomitant anticancer chemotherapies

by Kevin Harrington, Hardev Pandha, Alan Melcher, David Mansfield, Johann De Bono, Victoria Roulstone, Christine White, James Spicer, Richard Vile, Sophia N Karagiannis, Robert J Harris, Katie Twigger
Published 2021-07-01

The PERK Inhibitor GSK2606414 Enhances Reovirus Infection in Head and Neck Squamous Cell Carcinoma via an ATF4-Dependent Mechanism

by Martin McLaughlin, Malin Pedersen, Victoria Roulstone, Katharina F. Bergerhoff, Henry G. Smith, Harriet Whittock, Joan N. Kyula, Magnus T. Dillon, Hardev S. Pandha, Richard Vile, Alan A. Melcher, Kevin J. Harrington
Published 2020-03-01

Oncolytic Immunotherapy for Bladder Cancer Using Coxsackie A21 Virus

by Nicola E. Annels, Mehreen Arif, Guy R. Simpson, Mick Denyer, Carla Moller-Levet, David Mansfield, Rachel Butler, Darren Shafren, Gough Au, Margaret Knowles, Kevin Harrington, Richard Vile, Alan Melcher, Hardev Pandha
Published 2018-06-01

Immunogenicity of self tumor associated proteins is enhanced through protein truncation

by Tim Kottke, Kevin G Shim, Vanesa Alonso-Camino, Shane Zaidi, Rosa Maria Diaz, Jose Pulido, Jill Thompson, Karishma R Rajani, Laura Evgin, Elizabeth Ilett, Hardev Pandha, Kevin Harrington, Peter Selby, Alan Melcher, Richard Vile
Published 2016-01-01

Oncolytic Herpes Simplex Virus Inhibits Pediatric Brain Tumor Migration and Invasion

by Julia V. Cockle, Anke Brüning-Richardson, Karen J. Scott, Jill Thompson, Timothy Kottke, Ewan Morrison, Azam Ismail, Angel M. Carcaboso, Ailsa Rose, Peter Selby, Joe Conner, Susan Picton, Susan Short, Richard Vile, Alan Melcher, Elizabeth Ilett
Published 2017-06-01

Oncolytic virus-derived type I interferon restricts CAR T cell therapy

by Laura Evgin, Amanda L. Huff, Phonphimon Wongthida, Jill Thompson, Tim Kottke, Jason Tonne, Matthew Schuelke, Katayoun Ayasoufi, Christopher B. Driscoll, Kevin G. Shim, Pierce Reynolds, Dileep D. Monie, Aaron J. Johnson, Matt Coffey, Sarah L. Young, Gary Archer, John Sampson, Jose Pulido, Luis Sanchez Perez, Richard Vile
Published 2020-06-01