Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus

by Luke Whitesell, Nicole Robbins, David S. Huang, Catherine A. McLellan, Tanvi Shekhar-Guturja, Emmanuelle V. LeBlanc, Catherine S. Nation, Raymond Hui, Ashley Hutchinson, Cathy Collins, Sharanya Chatterjee, Richard Trilles, Jinglin L. Xie, Damian J. Krysan, Susan Lindquist, John A. Porco, Utpal Tatu, Lauren E. Brown, Juan Pizarro, Leah E. Cowen
Published 2019-01-01

An oxindole efflux inhibitor potentiates azoles and impairs virulence in the fungal pathogen Candida auris

by Kali R. Iyer, Kaddy Camara, Martin Daniel-Ivad, Richard Trilles, Sheila M. Pimentel-Elardo, Jen L. Fossen, Karen Marchillo, Zhongle Liu, Shakti Singh, José F. Muñoz, Sang Hu Kim, John A. Porco, Christina A. Cuomo, Noelle S. Williams, Ashraf S. Ibrahim, John E. Edwards, David R. Andes, Justin R. Nodwell, Lauren E. Brown, Luke Whitesell, Nicole Robbins, Leah E. Cowen
Published 2020-12-01