The dimerization domain in DapE enzymes is required for catalysis.

by Boguslaw Nocek, Anna Starus, Magdalena Makowska-Grzyska, Blanca Gutierrez, Stephen Sanchez, Robert Jedrzejczak, Jamey C Mack, Kenneth W Olsen, Andrzej Joachimiak, Richard C Holz
Published 2014-01-01

Indoline-6-Sulfonamide Inhibitors of the Bacterial Enzyme DapE

by Cory T. Reidl, Tahirah K. Heath, Iman Darwish, Rachel M. Torrez, Maxwell Moore, Elliot Gild, Boguslaw P. Nocek, Anna Starus, Richard C. Holz, Daniel P. Becker
Published 2020-09-01

Practical spectrophotometric assay for the dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase, a potential antibiotic target.

by Tahirah K Heath, Marlon R Lutz, Cory T Reidl, Estefany R Guzman, Claire A Herbert, Boguslaw P Nocek, Richard C Holz, Kenneth W Olsen, Miguel A Ballicora, Daniel P Becker
Published 2018-01-01