Mitochondria-targeted paraquat and metformin mediate ROS production to induce multiple pathways of retrograde signaling: A dose-dependent phenomenon

by Anindya Roy Chowdhury, Jacek Zielonka, Balaraman Kalyanaraman, Richard C. Hartley, Michael P. Murphy, Narayan G. Avadhani
Published 2020-09-01

Detection of changes in mitochondrial hydrogen sulfide in vivo in the fish model Poecilia mexicana (Poeciliidae)

by Gigi Y. Lau, Nicholas Barts, Richard C. Hartley, Michael Tobler, Jeffrey G. Richards, Michael P. Murphy, Sabine Arndt
Published 2019-05-01

Characterisation of the biflavonoid hinokiflavone as a pre-mRNA splicing modulator that inhibits SENP

by Andrea Pawellek, Ursula Ryder, Triin Tammsalu, Lewis J King, Helmi Kreinin, Tony Ly, Ronald T Hay, Richard C Hartley, Angus I Lamond
Published 2017-09-01

Enhancing the Mitochondrial Uptake of Phosphonium Cations by Carboxylic Acid Incorporation

by Laura Pala, Hans M. Senn, Stuart T. Caldwell, Tracy A. Prime, Stefan Warrington, Thomas P. Bright, Hiran A. Prag, Claire Wilson, Michael P. Murphy, Michael P. Murphy, Richard C. Hartley
Published 2020-09-01

Targeting Methylglyoxal in Diabetic Kidney Disease Using the Mitochondria-Targeted Compound MitoGamide

by Sih Min Tan, Runa S. J. Lindblom, Mark Ziemann, Adrienne Laskowski, Cesare Granata, Matthew Snelson, Vicki Thallas-Bonke, Assam El-Osta, Carlos D. Baeza-Garza, Stuart T. Caldwell, Richard C. Hartley, Thomas Krieg, Mark E. Cooper, Michael P. Murphy, Melinda T. Coughlan
Published 2021-04-01

Targeting succinate dehydrogenase with malonate ester prodrugs decreases renal ischemia reperfusion injury

by Timothy E. Beach, Hiran A. Prag, Laura Pala, Angela Logan, Margaret M. Huang, Anja V. Gruszczyk, Jack L. Martin, Krishnaa Mahbubani, Mazin O. Hamed, Sarah A. Hosgood, Michael L. Nicholson, Andrew M. James, Richard C. Hartley, Michael P. Murphy, Kourosh Saeb-Parsy
Published 2020-09-01