Threshold for Pre-existing Antibody Levels Limiting Transduction Efficiency of Systemic rAAV9 Gene Delivery: Relevance for Translation

by Aaron S. Meadows, Ricardo J. Pineda, Laurie Goodchild, Tierra A. Bobo, Haiyan Fu
Published 2019-06-01

Effective Depletion of Pre-existing Anti-AAV Antibodies Requires Broad Immune Targeting

by Victoria M. Velazquez, Aaron S. Meadows, Ricardo J. Pineda, Marybeth Camboni, Douglas M. McCarty, Haiyan Fu
Published 2017-03-01

Targeting Root Cause by Systemic scAAV9-hIDS Gene Delivery: Functional Correction and Reversal of Severe MPS II in Mice

by Haiyan Fu, Kim Zaraspe, Naoko Murakami, Aaron S. Meadows, Ricardo J. Pineda, Douglas M. McCarty, Joseph Muenzer
Published 2018-09-01