The PDZ-binding motif of severe acute respiratory syndrome coronavirus envelope protein is a determinant of viral pathogenesis.

by Jose M Jimenez-Guardeño, Jose L Nieto-Torres, Marta L DeDiego, Jose A Regla-Nava, Raul Fernandez-Delgado, Carlos Castaño-Rodriguez, Luis Enjuanes
Published 2014-08-01

MERS-CoV 4b protein interferes with the NF-κB-dependent innate immune response during infection.

by Javier Canton, Anthony R Fehr, Raúl Fernandez-Delgado, Francisco J Gutierrez-Alvarez, Maria T Sanchez-Aparicio, Adolfo García-Sastre, Stanley Perlman, Luis Enjuanes, Isabel Sola
Published 2018-01-01

Identification of the Mechanisms Causing Reversion to Virulence in an Attenuated SARS-CoV for the Design of a Genetically Stable Vaccine.

by Jose M Jimenez-Guardeño, Jose A Regla-Nava, Jose L Nieto-Torres, Marta L DeDiego, Carlos Castaño-Rodriguez, Raul Fernandez-Delgado, Stanley Perlman, Luis Enjuanes
Published 2015-10-01

Severe acute respiratory syndrome coronavirus envelope protein ion channel activity promotes virus fitness and pathogenesis.

by Jose L Nieto-Torres, Marta L DeDiego, Carmina Verdiá-Báguena, Jose M Jimenez-Guardeño, Jose A Regla-Nava, Raul Fernandez-Delgado, Carlos Castaño-Rodriguez, Antonio Alcaraz, Jaume Torres, Vicente M Aguilella, Luis Enjuanes
Published 2014-05-01

Forest restoration in a fog oasis: evidence indicates need for cultural awareness in constructing the reference.

by Luís Balaguer, Rosa Arroyo-García, Percy Jiménez, María Dolores Jiménez, Luís Villegas, Irene Cordero, Rafael Rubio de Casas, Raúl Fernández-Delgado, María Eugenia Ron, Esteban Manrique, Pablo Vargas, Emilio Cano, José J Pueyo, James Aronson
Published 2011-01-01

Role of Severe Acute Respiratory Syndrome Coronavirus Viroporins E, 3a, and 8a in Replication and Pathogenesis

by Carlos Castaño-Rodriguez, Jose M. Honrubia, Javier Gutiérrez-Álvarez, Marta L. DeDiego, Jose L. Nieto-Torres, Jose M. Jimenez-Guardeño, Jose A. Regla-Nava, Raul Fernandez-Delgado, Carmina Verdia-Báguena, Maria Queralt-Martín, Grazyna Kochan, Stanley Perlman, Vicente M. Aguilella, Isabel Sola, Luis Enjuanes
Published 2018-05-01

A conserved immunogenic and vulnerable site on the coronavirus spike protein delineated by cross-reactive monoclonal antibodies

by Chunyan Wang, Rien van Haperen, Javier Gutiérrez-Álvarez, Wentao Li, Nisreen M. A. Okba, Irina Albulescu, Ivy Widjaja, Brenda van Dieren, Raul Fernandez-Delgado, Isabel Sola, Daniel L. Hurdiss, Olalekan Daramola, Frank Grosveld, Frank J. M. van Kuppeveld, Bart L. Haagmans, Luis Enjuanes, Dubravka Drabek, Berend-Jan Bosch
Published 2021-03-01