Conformation dependent monoclonal antibodies distinguish different replicating strains or conformers of prefibrillar Aβ oligomers

by Yeung Stephen, Pensalfini Anna, Albay Ricardo, Wu Jessica, Lukacsovich Tamas, Rasool Suhail, Breydo Leonid, Canto Isabel, Kayed Rakez, Head Elizabeth, Marsh J Lawrence, Glabe Charles
Published 2010-12-01

Vaccination with a non-human random sequence amyloid oligomer mimic results in improved cognitive function and reduced plaque deposition and micro hemorrhage in Tg2576 mice

by Rasool Suhail, Albay Ricardo, Martinez-Coria Hilda, Breydo Leonid, Wu Jessica, Milton Saskia, Misra Sunit, Tran Andy, Pensalfini Anna, Laferla Frank, Kayed Rakez, Glabe Charles G
Published 2012-08-01

Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers

by Rasool Suhail, Thompson Jennifer L, Breydo Leonid, Wu Jessica, Margol Lawrence, Necula Mihaela, Cotman Carl W, Saing Tommy, Sarsoza Floyd, Head Elizabeth, Kayed Rakez, Gurlo Tatyana, Butler Peter, Glabe Charles G
Published 2007-09-01