Interleukin-4 Protects Dopaminergic Neurons In vitro but Is Dispensable for MPTP-Induced Neurodegeneration In vivo

by Laura Hühner, Jennifer Rilka, Ralf Gilsbach, Xiaolai Zhou, Xiaolai Zhou, Venissa Machado, Björn Spittau
Published 2017-03-01

5'-Hydroxymethylcytosine Precedes Loss of CpG Methylation in Enhancers and Genes Undergoing Activation in Cardiomyocyte Maturation.

by David K Kranzhöfer, Ralf Gilsbach, Björn A Grüning, Rolf Backofen, Thomas G Nührenberg, Lutz Hein
Published 2016-01-01

A hierarchical regulatory network analysis of the vitamin D induced transcriptome reveals novel regulators and complete VDR dependency in monocytes

by Timothy Warwick, Marcel H. Schulz, Stefan Günther, Ralf Gilsbach, Antonio Neme, Carsten Carlberg, Ralf P. Brandes, Sabine Seuter
Published 2021-03-01

Cardiac Myocyte De Novo DNA Methyltransferases 3a/3b Are Dispensable for Cardiac Function and Remodeling after Chronic Pressure Overload in Mice.

by Thomas G Nührenberg, Nils Hammann, Tilman Schnick, Sebastian Preißl, Anika Witten, Monika Stoll, Ralf Gilsbach, Franz-Josef Neumann, Lutz Hein
Published 2015-01-01

DNA methylation signatures follow preformed chromatin compartments in cardiac myocytes

by Stephan Nothjunge, Thomas G. Nührenberg, Björn A. Grüning, Stefanie A. Doppler, Sebastian Preissl, Martin Schwaderer, Carolin Rommel, Markus Krane, Lutz Hein, Ralf Gilsbach
Published 2017-11-01

Uncontrolled Diabetes Mellitus Has No Major Influence on the Platelet Transcriptome

by Thomas G. Nührenberg, Marco Cederqvist, Federico Marini, Christian Stratz, Björn A. Grüning, Dietmar Trenk, Harald Binder, Ralf Gilsbach, Franz-Josef Neumann, Lutz Hein
Published 2018-01-01

Increased expression of the auxiliary beta(2)-subunit of ventricular L-type Ca(2)+ channels leads to single-channel activity characteristic of heart failure.

by Roger Hullin, Jan Matthes, Sibylle von Vietinghoff, Ilona Bodi, Marta Rubio, Karen D'Souza, Ismail Friedrich Khan, Dennis Rottländer, Uta C Hoppe, Paul Mohacsi, Eva Schmitteckert, Ralf Gilsbach, Moritz Bünemann, Lutz Hein, Arnold Schwartz, Stefan Herzig
Published 2007-03-01

miR-128a Acts as a Regulator in Cardiac Development by Modulating Differentiation of Cardiac Progenitor Cell Populations

by Sarah C. Hoelscher, Theresia Stich, Anne Diehm, Harald Lahm, Martina Dreßen, Zhong Zhang, Irina Neb, Zouhair Aherrahrou, Jeanette Erdmann, Heribert Schunkert, Gianluca Santamaria, Giovanni Cuda, Ralf Gilsbach, Lutz Hein, Rüdiger Lange, David Hassel, Markus Krane, Stefanie A. Doppler
Published 2020-02-01

Distinct epigenetic programs regulate cardiac myocyte development and disease in the human heart in vivo

by Ralf Gilsbach, Martin Schwaderer, Sebastian Preissl, Björn A. Grüning, David Kranzhöfer, Pedro Schneider, Thomas G. Nührenberg, Sonia Mulero-Navarro, Dieter Weichenhan, Christian Braun, Martina Dreßen, Adam R. Jacobs, Harald Lahm, Torsten Doenst, Rolf Backofen, Markus Krane, Bruce D. Gelb, Lutz Hein
Published 2018-01-01