BACE1 Inhibition Using 2’-OMePS Steric Blocking Antisense Oligonucleotides

by Madhuri Chakravarthy, Rakesh N Veedu
Published 2019-09-01

Radiolabeling of Nucleic Acid Aptamers for Highly Sensitive Disease-Specific Molecular Imaging

by Leila Hassanzadeh, Suxiang Chen, Rakesh N. Veedu
Published 2018-10-01

Development of Novel antimiRzymes for Targeted Inhibition of miR-21 Expression in Solid Cancer Cells

by Leon M. Larcher, Tao Wang, Rakesh N. Veedu
Published 2019-07-01

Recent Advances in Oligonucleotide Therapeutics in Oncology

by Haoyu Xiong, Rakesh N. Veedu, Sarah D. Diermeier
Published 2021-03-01

Efficient Epidermal Growth Factor Receptor Targeting Oligonucleotide as a Potential Molecule for Targeted Cancer Therapy

by Tao Wang, Svetlana Philippovich, Jun Mao, Rakesh N. Veedu
Published 2019-09-01

Development of Novel Chemically-Modified Nucleic Acid Molecules for Efficient Inhibition of Human <i>MAPT</i> Gene Expression

by Madhuri Chakravarthy, Suxiang Chen, Tao Wang, Rakesh N. Veedu
Published 2020-06-01

Novel Chemically-modified DNAzyme targeting Integrin alpha-4 RNA transcript as a potential molecule to reduce inflammation in multiple sclerosis

by Madhuri Chakravarthy, May T. Aung-Htut, Bao T. Le, Rakesh N. Veedu
Published 2017-05-01

Computational investigation of locked nucleic acid (LNA) nucleotides in the active sites of DNA polymerases by molecular docking simulations.

by Vasanthanathan Poongavanam, Praveen K Madala, Torben Højland, Rakesh N Veedu
Published 2014-01-01

Systematic Screening of Commonly Used Commercial Transfection Reagents towards Efficient Transfection of Single-Stranded Oligonucleotides

by Tao Wang, Leon M. Larcher, Lixia Ma, Rakesh N. Veedu
Published 2018-10-01

Therapeutically Significant MicroRNAs in Primary and Metastatic Brain Malignancies

by Akilandeswari A. Balachandran, Leon M. Larcher, Suxiang Chen, Rakesh N. Veedu
Published 2020-09-01

Amplification and Re-Generation of LNA-Modified Libraries

by Jesper Wengel, Birte Vester, Lykke H. Hansen, Rakesh N. Veedu, Holger Doessing
Published 2012-11-01

Construction of a Bivalent Thrombin Binding Aptamer and Its Antidote with Improved Properties

by Quintin W. Hughes, Bao T. Le, Grace Gilmore, Ross I. Baker, Rakesh N. Veedu
Published 2017-10-01

Rational Design of Short Locked Nucleic Acid-Modified 2′-O-Methyl Antisense Oligonucleotides for Efficient Exon-Skipping In Vitro

by Bao T. Le, Abbie M. Adams, Susan Fletcher, Stephen D. Wilton, Rakesh N. Veedu
Published 2017-12-01

Synthesis of a Morpholino Nucleic Acid (MNA)-Uridine Phosphoramidite, and Exon Skipping Using MNA/2′-O-Methyl Mixmer Antisense Oligonucleotide

by Suxiang Chen, Bao T. Le, Kamal Rahimizadeh, Khalil Shaikh, Narinder Mohal, Rakesh N. Veedu
Published 2016-11-01

Alpha-<span style="font-variant: small-caps">l</span>-Locked Nucleic Acid-Modified Antisense Oligonucleotides Induce Efficient Splice Modulation In Vitro

by Prithi Raguraman, Tao Wang, Lixia Ma, Per Trolle Jørgensen, Jesper Wengel, Rakesh N. Veedu
Published 2020-03-01

Rapid one-step selection method for generating nucleic acid aptamers: development of a DNA aptamer against α-bungarotoxin.

by Lasse H Lauridsen, Hadi A Shamaileh, Stacey L Edwards, Elena Taran, Rakesh N Veedu
Published 2012-01-01

Efficient reverse transcription using locked nucleic acid nucleotides towards the evolution of nuclease resistant RNA aptamers.

by Lucile Crouzier, Camille Dubois, Stacey L Edwards, Lasse H Lauridsen, Jesper Wengel, Rakesh N Veedu
Published 2012-01-01

Antisense Oligonucleotides Targeting Angiogenic Factors as Potential Cancer Therapeutics

by Bao T. Le, Prithi Raguraman, Tamer R. Kosbar, Susan Fletcher, Steve D. Wilton, Rakesh N. Veedu
Published 2019-03-01

Development of Cell-Specific Aptamers: Recent Advances and Insight into the Selection Procedures

by Kamal Rahimizadeh, Hadi AlShamaileh, Milena Fratini, Madhuri Chakravarthy, Michelle Stephen, Sarah Shigdar, Rakesh N. Veedu
Published 2017-11-01

Consequences of Making the Inactive Active Through Changes in Antisense Oligonucleotide Chemistries

by Khine Zaw, Khine Zaw, Kane Greer, Kane Greer, May Thandar Aung-Htut, May Thandar Aung-Htut, Chalermchai Mitrpant, Chalermchai Mitrpant, Rakesh N. Veedu, Rakesh N. Veedu, Sue Fletcher, Sue Fletcher, Steve D. Wilton, Steve D. Wilton
Published 2019-12-01