Antibody-Dependent Enhancement: A Challenge for Developing a Safe Dengue Vaccine

by Rahul Shukla, Viswanathan Ramasamy, Rajgokul K. Shanmugam, Richa Ahuja, Navin Khanna
Published 2020-10-01

Zika virus envelope nanoparticle antibodies protect mice without risk of disease enhancement

by Rahul Shukla, Rajgokul K. Shanmugam, Viswanathan Ramasamy, Upasana Arora, Gaurav Batra, Joshua A. Acklin, Florian Krammer, Jean K. Lim, Sathyamangalam Swaminathan, Navin Khanna
Published 2020-04-01

Dengue and Zika virus infections are enhanced by live attenuated dengue vaccine but not by recombinant DSV4 vaccine candidate in mouse models

by Rahul Shukla, Hemalatha Beesetti, Julia A. Brown, Richa Ahuja, Viswanathan Ramasamy, Rajgokul K. Shanmugam, Ankur Poddar, Gaurav Batra, Florian Krammer, Jean K. Lim, Sachin Kale, Altaf A. Lal, Sathyamangalam Swaminathan, Navin Khanna
Published 2020-10-01

A tetravalent virus-like particle vaccine designed to display domain III of dengue envelope proteins induces multi-serotype neutralizing antibodies in mice and macaques which confe...

by Viswanathan Ramasamy, Upasana Arora, Rahul Shukla, Ankur Poddar, Rajgokul K Shanmugam, Laura J White, Melissa M Mattocks, Rajendra Raut, Ashiya Perween, Poornima Tyagi, Aravinda M de Silva, Siddhartha K Bhaumik, Murali Krishna Kaja, François Villinger, Rafi Ahmed, Robert E Johnston, Sathyamangalam Swaminathan, Navin Khanna
Published 2018-01-01