Disruption of Cell Adhesion and Cytoskeletal Networks by Thiol-Functionalized Silica-Coated Iron Oxide Nanoparticles

by Karel Královec, Lucie Melounková, Marcela Slováková, Nikola Mannová, Miloš Sedlák, Jan Bartáček, Radim Havelek
Published 2020-12-01

Chemical and Biological Aspects of Montanine-Type Alkaloids Isolated from Plants of the Amaryllidaceae Family

by Darja Koutová, Negar Maafi, Radim Havelek, Lubomír Opletal, Gerald Blunden, Martina Řezáčová, Lucie Cahlíková
Published 2020-05-01

Effective Method of Purification of Betulin from Birch Bark: The Importance of Its Purity for Scientific and Medicinal Use.

by Pavel Šiman, Alžběta Filipová, Alžběta Filipová, Alena Tichá, Mohamed Niang, Aleš Bezrouk, Radim Havelek
Published 2016-01-01

Pancracine, a Montanine-Type Amaryllidaceae Alkaloid, Inhibits Proliferation of A549 Lung Adenocarcinoma Cells and Induces Apoptotic Cell Death in MOLT-4 Leukemic Cells

by Darja Koutová, Radim Havelek, Eva Peterová, Darina Muthná, Karel Královec, Kateřina Breiterová, Lucie Cahlíková, Martina Řezáčová
Published 2021-06-01

The effect of sodium butyrate and cisplatin on expression of EMT markers.

by Alena Mrkvicova, Marcela Chmelarova, Eva Peterova, Radim Havelek, Ivana Baranova, Petra Kazimirova, Emil Rudolf, Martina Rezacova
Published 2019-01-01

Bersavine: A Novel Bisbenzylisoquinoline Alkaloid with Cytotoxic, Antiproliferative and Apoptosis-Inducing Effects on Human Leukemic Cells

by Darja Koutova, Monika Kulhava, Radim Havelek, Martina Majorosova, Karel Královec, Klara Habartova, Anna Hošťálková, Lubomír Opletal, Lucie Cahlikova, Martina Řezáčová
Published 2020-02-01

Amaryllidaceae Alkaloids of Different Structural Types from <i>Narcissus</i> L. cv. Professor Einstein and Their Cytotoxic Activity

by Kateřina Breiterová, Darja Koutová, Jana Maříková, Radim Havelek, Jiří Kuneš, Martina Majorošová, Lubomír Opletal, Anna Hošťálková, Jaroslav Jenčo, Martina Řezáčová, Lucie Cahlíková
Published 2020-01-01

Derivatives of the β-Crinane Amaryllidaceae Alkaloid Haemanthamine as Multi-Target Directed Ligands for Alzheimer’s Disease

by Eliška Kohelová, Rozálie Peřinová, Negar Maafi, Jan Korábečný, Daniela Hulcová, Jana Maříková, Tomáš Kučera, Loreto Martínez González, Martina Hrabinova, Katarina Vorčáková, Lucie Nováková, Angela De Simone, Radim Havelek, Lucie Cahlíková
Published 2019-04-01

Substituted Piperazines as Novel Potential Radioprotective Agents

by Alzbeta Filipova, Jan Marek, Radim Havelek, Jaroslav Pejchal, Marcela Jelicova, Jana Cizkova, Martina Majorosova, Lubica Muckova, Tomas Kucera, Lukas Prchal, Miroslav Psotka, Natalie Zivna, Darja Koutova, Zuzana Sinkorova, Martina Rezacova, Ales Tichy
Published 2020-01-01