Nef decreases HIV-1 sensitivity to neutralizing antibodies that target the membrane-proximal external region of TMgp41.

by Rachel P J Lai, Jin Yan, Jonathan Heeney, Myra O McClure, Heinrich Göttlinger, Jeremy Luban, Massimo Pizzato
Published 2011-12-01

Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity

by Ursula K. Rohlwink, Anthony Figaji, Katalin A. Wilkinson, Stuart Horswell, Abdul K. Sesay, Armin Deffur, Nico Enslin, Regan Solomons, Ronald Van Toorn, Brian Eley, Michael Levin, Robert J. Wilkinson, Rachel P. J. Lai
Published 2019-08-01

Genetic imprint of vaccination on simian/human immunodeficiency virus type 1 transmitted viral genomes in rhesus macaques.

by Mariana Varela, Ernst Verschoor, Rachel P J Lai, Joseph Hughes, Petra Mooj, Trevelyan J McKinley, Timothy J Fitzmaurice, Lisa Landskron, Brian J Willett, Simon D W Frost, Willy M Bogers, Jonathan L Heeney
Published 2013-01-01

Mixed adjuvant formulations reveal a new combination that elicit antibody response comparable to Freund's adjuvants.

by Rachel P J Lai, Michael S Seaman, Paul Tonks, Frank Wegmann, David J Seilly, Simon D W Frost, Celia C LaBranche, David C Montefiori, Antu K Dey, Indresh K Srivastava, Quentin Sattentau, Susan W Barnett, Jonathan L Heeney
Published 2012-01-01

Study protocol for a phase 2A trial of the safety and tolerability of increased dose rifampicin and adjunctive linezolid, with or without aspirin, for HIV-associated tuberculous me...

by Angharad G. Davis, Sean Wasserman, Mpumi Maxebengula, Cari Stek, Marise Bremer, Remy Daroowala, Saalikha Aziz, Rene Goliath, Stephani Stegmann, Sonya Koekemoer, Amanda Jackson, Louise Lai Sai, Yakub Kadernani, Thandi Sihoyiya, C.Jason Liang, Lori Dodd, Paolo Denti, Thomas Crede, Jonathan Naude, Patryk Szymanski, Yakoob Vallie, Ismail Banderker, Shiraz Moosa, Peter Raubenheimer, Rachel P.J. Lai, John Joska, Sam Nightingale, Anna Dreyer, Gerda Wahl, Curtis Offiah, Isak Vorster, Sally Candy, Frances Robertson, Ernesta Meintjes, Gary Maartens, John Black, Graeme Meintjes, Robert J. Wilkinson
Published 2021-06-01