Indirect sexual selection drives rapid sperm protein evolution in abalone

by Damien Beau Wilburn, Lisa M Tuttle, Rachel E Klevit, Willie J Swanson
Published 2019-12-01

Interplay of disordered and ordered regions of a human small heat shock protein yields an ensemble of ‘quasi-ordered’ states

by Amanda F Clouser, Hannah ER Baughman, Benjamin Basanta, Miklos Guttman, Abhinav Nath, Rachel E Klevit
Published 2019-10-01

Mediator subunit Med15 dictates the conserved “fuzzy” binding mechanism of yeast transcription activators Gal4 and Gcn4

by Lisa M. Tuttle, Derek Pacheco, Linda Warfield, Damien B. Wilburn, Steven Hahn, Rachel E. Klevit
Published 2021-04-01

Cbl interacts with multiple E2s in vitro and in cells.

by Mariya S Liyasova, Ke Ma, Donna Voeller, Philip E Ryan, Jinqiu Chen, Rachel E Klevit, Stanley Lipkowitz
Published 2019-01-01

Gcn4-Mediator Specificity Is Mediated by a Large and Dynamic Fuzzy Protein-Protein Complex

by Lisa M. Tuttle, Derek Pacheco, Linda Warfield, Jie Luo, Jeff Ranish, Steven Hahn, Rachel E. Klevit
Published 2018-03-01

A conserved histidine modulates HSPB5 structure to trigger chaperone activity in response to stress-related acidosis

by Ponni Rajagopal, Eric Tse, Andrew J Borst, Scott P Delbecq, Lei Shi, Daniel R Southworth, Rachel E Klevit
Published 2015-05-01

Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination

by Kedar Puvar, Shalini Iyer, Jiaqi Fu, Sebastian Kenny, Kristos I. Negrón Terón, Zhao-Qing Luo, Peter S. Brzovic, Rachel E. Klevit, Chittaranjan Das
Published 2020-05-01

Acidic pH and divalent cation sensing by PhoQ are dispensable for systemic salmonellae virulence

by Kevin G Hicks, Scott P Delbecq, Enea Sancho-Vaello, Marie-Pierre Blanc, Katja K Dove, Lynne R Prost, Margaret E Daley, Kornelius Zeth, Rachel E Klevit, Samuel I Miller
Published 2015-05-01

Toggle switch residues control allosteric transitions in bacterial adhesins by participating in a concerted repacking of the protein core.

by Dagmara I Kisiela, Pearl Magala, Gianluca Interlandi, Laura A Carlucci, Angelo Ramos, Veronika Tchesnokova, Benjamin Basanta, Vladimir Yarov-Yarovoy, Hovhannes Avagyan, Anahit Hovhannisyan, Wendy E Thomas, Ronald E Stenkamp, Rachel E Klevit, Evgeni V Sokurenko
Published 2021-04-01

Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1

by Joseph S Harrison, Evan M Cornett, Dennis Goldfarb, Paul A DaRosa, Zimeng M Li, Feng Yan, Bradley M Dickson, Angela H Guo, Daniel V Cantu, Lilia Kaustov, Peter J Brown, Cheryl H Arrowsmith, Dorothy A Erie, Michael B Major, Rachel E Klevit, Krzysztof Krajewski, Brian Kuhlman, Brian D Strahl, Scott B Rothbart
Published 2016-09-01