High Throughput Screening of FDA-Approved Drug Library Reveals the Compounds that Promote IRF3-Mediated Pro-Apoptotic Pathway Inhibit Virus Replication

by Anna Glanz, Karan Chawla, Stephanie Fabry, Gayatri Subramanian, Julie Garcia, Bryanna Jay, Jacob Ciricillo, Ritu Chakravarti, R. Travis Taylor, Saurabh Chattopadhyay
Published 2020-04-01

Interferon signaling in Peromyscus leucopus confers a potent and specific restriction to vector-borne flaviviruses.

by Adaeze O Izuogu, Kristin L McNally, Stephen E Harris, Brian H Youseff, John B Presloid, Christopher Burlak, Jason Munshi-South, Sonja M Best, R Travis Taylor
Published 2017-01-01

TRAF6 Plays a Proviral Role in Tick-Borne Flavivirus Infection through Interaction with the NS3 Protease

by Brian H. Youseff, Thomas G. Brewer, Kristin L. McNally, Adaeze O. Izuogu, Kirk J. Lubick, John B. Presloid, Saad Alqahtani, Saurabh Chattopadhyay, Sonja M. Best, Xiche Hu, R. Travis Taylor
Published 2019-05-01

Identification of candidate repurposable drugs to combat COVID-19 using a signature-based approach

by Sinead M. O’Donovan, Ali Imami, Hunter Eby, Nicholas D. Henkel, Justin Fortune Creeden, Sophie Asah, Xiaolu Zhang, Xiaojun Wu, Rawan Alnafisah, R. Travis Taylor, James Reigle, Alexander Thorman, Behrouz Shamsaei, Jarek Meller, Robert E. McCullumsmith
Published 2021-02-01

TRIM5α Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation

by Abhilash I. Chiramel, Nicholas R. Meyerson, Kristin L. McNally, Rebecca M. Broeckel, Vanessa R. Montoya, Omayra Méndez-Solís, Shelly J. Robertson, Gail L. Sturdevant, Kirk J. Lubick, Vinod Nair, Brian H. Youseff, Robin M. Ireland, Catharine M. Bosio, Kyusik Kim, Jeremy Luban, Vanessa M. Hirsch, R. Travis Taylor, Fadila Bouamr, Sara L. Sawyer, Sonja M. Best
Published 2019-06-01